Association of Low Serum Maresin-1 Levels with Hepatocellular Carcinoma in Cirrhotic Liver.

Background: Maresin-1 (MaR1) is a macrophage-derived antiinflammatory lipid mediator that negatively regulates oxidative and proinflammatory cytokines and also restores integrity in various tissues after inflammation. Non-resolving inflammation is known to have an important role in the pathogenesis of hepatocellular carcinoma (HCC). The aim of the present study was to evaluate the role of MaR1 in pathogenesis and early diagnosis of HCC.

Could maternal serum MFG-E8 level predict adverse first trimester pregnancy outcome? A preliminary study.

Background: Milk fat globule-epidermal growth factor 8 (MFG-E8) is expressed in the endometrial epithelium and its expression increases during the implantation process. Due to this knowledge, we aimed to investigate the maternal serum MFG-E8 levels on both healthy pregnant women in the first trimester and pregnant women complicated with missed abortion and threatened abortion in the first trimester.

Methods: This prospective, cross-sectional study was conducted in a tertiary referral hospital, department of obstetrics between July 2020 and February 2021 after ethical committee approval.