Aims: To establish reference values of semen parameters in a residential, geographic, and age representative sample of healthy Chinese men.
Methods: From a national study of 1,191 healthy Chinese men, semen samples were analyzed from 105 subjects whose wives or partners were pregnant within the 12 months prior to the date when the semen sample was taken.
Results: The means, fifth percentiles, and percentages lower than the WHO criteria for semen parameters were, respectively: 75.
The proliferative activity of neural precursors from the subventricular zone (SVZ) was investigated after a unilateral lesion was formed in the nigrostriatal pathway in adult rats. The lesion was formed by unilateral injection of 6-hydroxydopamine (6-OHDA) into the nigrostriatal pathway, and then bromodeoxyuridine (BrdU) was injected (ip) for 4 days or 2 weeks 10 days after the lesion was formed. The rats were killed, and the brain sections were immunohistochemically stained to detect the expression of BrdU, polysialylated neural-cell-adhesion molecule (PSA-NCAM), glial fibrillary acidic protein (GFAP) and tyrosine hydroxylase (TH) in the SVZ and the striatum (STR).
View Article and Find Full Text PDFEffects of scorpion venom active polypeptide (SVAP) from scorpion venom of Buthus Martensii Karsch of Chinese on platelet aggregation in ex vivo and vitro in rabbits, thrombosis in carotid artery of rats and plasma 6-keto-PG F1alpha and TXB2 in rats were studied by the turbidimetry, the duplicated thrombosis model by electrostimulation and RIA, respectively. The results showed that SVAP 0.125, 0.
View Article and Find Full Text PDFThe calcitonin receptor-like receptor (CRLR) and the orphan receptor RDC-1 have been proposed to be calcitonin gene-related peptide type 1 (CGRP1) receptors, and receptor activity-modifying proteins (RAMPs) determine the ligand specificity of CRLR. Coexpression of RAMP1 and CRLR resulted in functional CGRP1 receptors; the complex of RAMP2 or RAMP3 and CRLR created functional adrenomedullin receptor. Although high levels of CGRP binding sites in the nucleus accumbens have been reported, little is known about the expression of these novel CGRP receptors.
View Article and Find Full Text PDFObjective: To review the progress in the study of chemical ingrediens, pharmacological effects and clinical application of Allium macrostemon Bunge.
Method: Documents of experimental and clinical study on A. macrostemon in recent 10 years were consulted and summarized.