Publications by authors named "Er Dan Luo"

Article Synopsis
  • - The human placenta is a crucial organ with various cell types that support fetal growth, substance exchange, and immune functions, making it essential for a healthy pregnancy.
  • - Abnormalities in placental cells can cause pregnancy issues, but the underlying mechanisms are still not fully understood; new technologies like single-cell and spatial transcriptomics have helped reveal cell diversity and interactions within the placenta.
  • - The review explores existing research on normal and disease-affected placentas, including conditions like preeclampsia and gestational diabetes, while also addressing the limitations of current studies and suggesting future research directions.
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Objective: Since coronary artery lesions (CALs) are the most severe complication of Kawasaki disease (KD), clinically speaking, early prediction of CALs is crucial. The authors aimed to investigate the predictive value of C-reactive protein (CRP) in predicting CALs in KD patients.

Methods: KD patients were divided into the CALs group and the non-CALs group.

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Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases in women of reproductive age and features complex pathological symptoms and mechanisms. Existing medical treatments have, to some extent, alleviated the deterioration of PCOS. However, these strategies only temporarily control symptoms, with a few side effects and no preventive effect.

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Objective: To investigate the optimal timing of initial intravenous immunoglobulin (IVIG) treatment in Kawasaki disease (KD) patients.

Methods: KD patients were classified as the early group (day 1-4), conventional group (day 5-7), conventional group (day 8-10), and late group (after day 10). Differences among the groups were analyzed by ANOVA and Chi-square analysis.

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Peptides have gained popularity in the global market during recent years and have been placed between small molecule drugs and biologics. However, little is known about the comprehensive landscape of peptide drugs in obstetrics and gynaecology. Herein, we analysed new peptide drug-related clinical trials in obstetrics and gynaecology registered on ClinicalTrials.

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