Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility.

Neurotrophin regulation of actin-dependent changes in growth cone motility may depend on the signaling of beta-actin mRNA transport. Formation of an RNP complex between the beta-actin mRNA zipcode sequence and Zipcode Binding Protein 1 (ZBP1) was required for its localization to growth cones. Antisense oligonucleotides to the zipcode inhibited formation of this RNP complex in vitro and the neurotrophin-induced localization of beta-actin mRNA and ZBP1 granules.

In vitro selection of the RNA aptamer against the Sialyl Lewis X and its inhibition of the cell adhesion.

Sialyl Lewis X (sLeX) is a tetra-saccharide glycoconjugate of membrane proteins. It acts as a ligand for the selectin proteins during cell adhesion of inflammatory process. Aberrant overexpression of sLeX is also a characteristic of various cancer cells, especially for highly malignant ones.

Polarization properties of cube-corner retroreflectors and their effects on signal strength and nonlinearity in heterodyne interferometers.

The polarization properties of solid-state cube-corner retroreflectors, which are uncoated glass or metal-coated glass on the reflecting surfaces, are examined analytically and compared. Experimental verifications are presented for the case of linearly polarized incident light. When the uncoated cube-corner is used in a heterodyne interferometer, the polarization properties reveal that the axial orientation of the corner reflector has an effect on the strength of the beat signal and the nonlinearity error.