A large-scale study of bone marrow involvement in patients with Hodgkin's lymphoma.

This study was designed to identify variables that can predict bone marrow involvement (BMI) in Hodgkin's lymphoma (HL), and to analyze the benefit of bilateral over unilateral bone marrow trephine biopsy (BMB). From 1982 to 2000, BMB had been performed at diagnosis in 1161 patients with HL who had been followed from the institutions participating in the Piemonte Hodgkin's Disease Registry. Six hundred and sixteen patients (53%) had received bilateral BMB, and the remaining 545 patients (47%) received unilateral BMB.

[The "Valle Belbo Project" for the prevention of ischemic heart disease: study design and correlations between alcohol and cardiovascular risk factors].

Background: The "Valle Belbo Project" is a primary prevention study on ischemic heart disease, aiming at identifying cardiovascular risk factors. Detailed data about the amount and kind of alcohol beverages used were assessed, too. The aims of the present study were to evaluate the prevalence of cardiovascular risk factors, and the relationships between alcohol and these factors.