Publications by authors named "Enzo Masci"
Article Synopsis
- The study looked at a new treatment called cSEMS for patients who had issues after liver transplants, specifically with narrow connections (anastomotic strictures).
- Researchers examined 91 patients over ten years and found that the treatment worked without serious problems, but some stents moved out of place.
- The main issue was that when the stents migrated, many patients needed more treatments, suggesting that better designs of stents could help prevent this problem.
Familial adenomatous polyposis (FAP) is an autosomal-dominant hereditary condition associated with germline mutations in the adenomatous polyposis coli gene. Patient management involves prophylactic surgery and intensive life-long endoscopic surveillance. Diet is a major concern for patients with FAP, who are generally free of symptoms before surgery but tend to have issues related to bowel function postoperatively.
View Article and Find Full Text PDFIntroduction: Fine-needle biopsy (FNB) has been suggested to provide better histological samples as compared to endoscopic ultrasound fine-needle aspiration (EUS-FNA). However, studies comparing EUS-FNA and EUS-FNB for pancreatic lesions reported contrasting results. The aim of this study was to compare the clinical performance of EUS-FNA versus EUS-FNB with the ProCore needle for the investigation of pancreatic lesions.
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- The survey aimed to evaluate infection control practices and outcomes in Digestive Endoscopy Units in Lombardy, a region severely affected by COVID-19.
- Most participating centers adapted their operations in line with recommendations, with a majority having necessary protective gear, but few had negative-pressure rooms.
- Higher COVID-19 rates were observed among endoscopists and nurses, indicating significant risks of viral spread in endoscopy settings, despite overall good adherence to safety guidelines.
After the lockdown during the emergency phase of the Covid-19 pandemic, we have to deal with phase 2, a period of uncertain duration, with a controlled and progressive return to normalization, in which we need to reconcile our work and our movements with the presence of the virus on our territory. Digestive endoscopic activity is a high-risk transmission procedure for Covid-19. The measures put in place to protect healthcare personnel and patients are stressful and "time-consuming" and lead to a reduction in the number of endoscopic procedures that can be performed.
View Article and Find Full Text PDFIntroduction: Endobronchial ultrasound (EBUS) is an endoscopic diagnostic procedure combining flexible fibrobronchoscopy with ultrasound techniques; it allows transbronchial needle aspiration biopsy for the diagnosis and staging of mediastinal masses. We present our preliminary experience with the use of the i-gel O supraglottic airway device for management of EBUS procedures.
Methods: An observational study on 39 patients who underwent EBUS under general anesthesia was performed.
Colorectal cancer (CRC) screening programs help diagnose cancer precursors and early cancers and help reduce CRC mortality. However, currently recommended tests, the fecal immunochemical test (FIT) and colonoscopy, have low uptake. There is therefore a pressing need for screening strategies that are minimally invasive and consequently more acceptable to patients, most likely blood based, to increase early CRC identification.
View Article and Find Full Text PDFPatients with familial adenomatous polyposis (FAP) depend on a lifelong endoscopic surveillance programme and prophylactic surgery, and usually suffer nutritional problems. Intestinal inflammation has been linked to both FAP and colorectal cancer. Epidemiological studies show a relationship between diet and inflammation.
View Article and Find Full Text PDFBackground: The most appropriate endo-therapeutic approach to biliary anastomotic strictures is yet to be defined.
Aim: To retrospectively report on the endo-therapy of duct-to-duct anastomotic strictures during 2013 in Italy.
Methods: Data were collected from 16 Endoscopy Units at the Italian Liver Transplantation Centers (BASALT study group).
Background And Objective: A new 20-gauge (G) biopsy needle with a core-trap technology has been developed with a large core size and enhanced flexibility. The aim of this multicenter study was to determine the feasibility, efficacy, and safety of EUS-guided fine-needle biopsy (EUS-FNB) with the new 20G needle in diagnosing subepithelial lesions (SELs).
Materials And Methods: Retrospectively collected data from consecutive patients with SELs undergoing EUS-FNB with the 20G needle at five centers were analyzed.
Background: Hemospray is a new endoscopic haemostatic powder that can be used in the management of upper gastrointestinal bleedings.
Aims: To assess the efficacy and safety of Hemospray as monotherapy for the treatment of acute upper gastrointestinal bleeding due to cancer.
Methods: The endoscopy databases of 3 Italian Endoscopic Units were reviewed retrospectively and 15 patients (8 males; mean age 74 years) were included in this study.
Aim: To determine the outcome of the management of iatrogenic gastrointestinal tract perforations treated by over-the-scope clip (OTSC) placement.
Methods: We retrospectively enrolled 20 patients (13 female and 7 male; mean age: 70.6 ± 9.
Aim: To investigate gastrointestinal complications associated with non-steroidal anti-inflammatory drug (NSAIDs) use in children.
Methods: A retrospective, multicenter study was conducted between January 2005 and January 2013, with the participation of 8 Italian pediatric gastroenterology centers. We collected all the cases of patients who refer to emergency room for suspected gastrointestinal bleeding following NSAIDs consumption, and underwent endoscopic evaluation.
Background: The guidewire biliary cannulation (GWC) technique may increase the cannulation rate and decrease the risk for post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. The aim of our multicenter prospective randomized controlled trial was to determine if the use of an atraumatic loop-tip guidewire reduces the rate of post-ERCP pancreatitis (PEP) compared with the standard contrast-assisted cannulation (CC) technique.
Methods: From June 2012 to December 2013, a total of 320 patients who had a naïve papilla and were referred for ERCP were randomly assigned to the GWC group (n = 160) or the CC group (n = 160).
Rectal syphilis is a rare expression of the widely recognised sexual transmitted disease, also known as the great imitator for its peculiarity of being confused with mild anorectal diseases because of its vague symptoms or believed rectal malignancy, with the concrete risk of overtreatment. We present the case of a male patient with primary rectal syphilis, firstly diagnosed as rectal cancer; the medical, radiological, and endoscopic features are discussed below.
View Article and Find Full Text PDFBackground: Chronic constipation is a risk factor of inadequate bowel preparation for colonoscopy; however, no large clinical trials have been performed in this subgroup of patients.
Aims: To compare bowel cleansing efficacy, tolerability and acceptability of 2-L polyethylene-glycol-citrate-simethicone (PEG-CS) plus 2-day bisacodyl (reinforced regimen) vs. 4-L PEG in patients with chronic constipation undergoing colonoscopy.
Introduction And Objectives: Acute gastrointestinal (GI) bleeding can lead from mild to immediately life-threatening clinical conditions. Upper GI bleeding (UGIB) is associated with a mortality of 6-10%. Spurting and oozing bleeding are associated with major risk of failure.
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- Hemospray TM (TC-325) is an innovative agent used in treating nonvariceal upper gastrointestinal bleeding (NVUGIB) in Europe, showing promising results in clinical settings.
- A study involving data from 10 European centers revealed that out of 63 patients treated, 87% achieved primary hemostasis, with a lower rebleeding rate of 15% in the following week.
- The findings suggest that TC-325 is effective both as a primary treatment and as a secondary option for patients who did not respond to initial therapies, demonstrating its versatility across various types of NVUGIB.