Cutaneous melanoma metastatic to the orbit: review of 15 cases.

Purpose: To describe the clinical features, management, and outcomes of 15 patients with cutaneous melanoma metastatic to the orbit. The authors review emerging treatments for metastatic melanoma and their ocular implications.

Methods: Retrospective chart review of 15 patients with orbital metastasis from cutaneous melanoma.

Association of LOC387715/ARMS2 (rs10490924) Gene Polymorphism with Age-Related Macular Degeneration in the Brazilian Population.

Background: An association between LOC387715/ARMS2 (rs10490924) gene polymorphism and AMD has been reported. The aim of this study was to evaluate whether this polymorphism is associated with AMD in a Brazilian cohort.

Materials And Methods: In total, 126 unrelated AMD patients (mean age 74.

Single-agent, minimal dose, minimal exposure intraarterial chemotherapy for retinoblastoma in a 4-month-old infant.

Purpose: To document minimal dose and minimal exposure of chemotherapy for unilateral retinoblastoma.

Methods: A 4-month-old infant developed leukocoria in the right eye and was found to have unilateral sporadic retinoblastoma.

Results: The right eye was classified as Group D retinoblastoma, with a single large tumor, moderate subretinal seeding, and total retinal detachment.

The seasick choroid: a finding on enhanced depth imaging spectral-domain optical coherence tomography of choroidal lymphoma.

Purpose: To describe previously unreported imaging features of choroidal lymphoma using enhanced depth imaging optical coherence tomography (OCT).

Methods: Enhanced depth imaging OCT was performed before and after the therapy.

Results: A 32-year-old white man with a 4-month history of blurred vision in the right eye was found to have a macular fold.

Effect of preoperative use of topical prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery: a randomized trial.

Purpose: To compare the effects of preoperative use of topical anti-inflammatory prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery.

Design: Randomized clinical trial.

Materials And Methods: This single-center, masked, randomized clinical study comprised 140 patients scheduled for cataract surgery.