Lower limit of adequate oxygen delivery for the maintenance of aerobic metabolism during cardiopulmonary bypass in neonates.

Background: The objective of cardiopulmonary bypass (CPB) is to maintain an adequate balance between oxygen delivery (Ḋo) and consumption. The critical Ḋo is that at which consumption becomes supply dependent. This study aimed to identify the critical Ḋo in neonates, who have higher metabolic rates than adults.