Publications by authors named "Enrique Querejeta-Villagomez"
Article Synopsis
- The thalamic reticular nucleus is crucial for processing information in thalamocortical neurons, influenced by GABAergic neurons and their connections with globus pallidus neurons.
- This study focused on the effects of damaging the globus pallidus on the electrical activity and molecular responses of the thalamic reticular nucleus in male rats.
- The results showed that the lesion increased neuron firing frequency and D4 receptor levels, but decreased the expression of the α3 subunit of GABAA receptors, indicating a complex regulatory role of the globus pallidus on thalamic neuron firing.
Putrescine, spermidine and spermine are natural compounds found in up to millimolar concentrations in eukaryotic and prokaryotic cells. At physiologic pH, the polyamines are protonated (+2, +3 and +4 charges), their polycationic properties lead to the assumption that they could affect physiological systems by binding to anionic sites of the cellular membrane and/or by modulating ion channels. At the cardiovascular level, their effects are not completely understood.
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