Can the cold pressor test predict future cardiovascular events in patients without demonstrated ischemic heart disease by SPECT?

Objective: To assess whether a cold pressor test (CPT) could help identify patients at a high risk of cardiovascular events in a population without known coronary artery disease (CAD) with a normal myocardial perfusion scintigraphy (MPS).

Methods: Our population consisted of 870 patients with a mean age of 59.3years with several CAD risk factors, having been referred for an MPS.