Publications by authors named "Enrique Molla Olmos"

(1) Objective. We aimed to demonstrate that the use of the ultrasound-guided technique facilitates peripheral venous cannulation as compared to the standard technique in patients with difficult access at emergency services. (2) Method.

View Article and Find Full Text PDF

Introduction: IDH1/2 wt glioblastoma (GB) represents the most lethal tumour of the central nervous system. Tumour vascularity is associated with overall survival (OS), and the clinical relevance of vascular markers, such as rCBV, has already been validated. Nevertheless, molecular and clinical factors may have different influences on the beneficial effect of a favourable vascular signature.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates how tumor blood flow, identified through perfusion MRI, and MGMT methylation status impact overall survival in glioblastoma patients.
  • It involved analyzing data from 96 patients to determine the influence of vascularity and MGMT methylation on survival rates, revealing that moderately vascularized tumors benefit from MGMT methylation.
  • The findings suggest that combining these two factors provides important insights for prognostic assessments, emphasizing the need to consider both in clinical studies to avoid bias.
View Article and Find Full Text PDF

Purpose: To evaluate the potential of 2D texture features extracted from magnetic resonance (MR) images for differentiating brain metastasis (BM) and glioblastomas (GBM) following a radiomics approach.

Methods: This retrospective study included 50 patients with BM and 50 with GBM who underwent T1-weighted MRI between December 2010 and January 2017. Eighty-eight rotation-invariant texture features were computed for each segmented lesion using six texture analysis methods.

View Article and Find Full Text PDF

Background: Glioblastoma (GBM) is the most aggressive primary brain tumor, characterized by a heterogeneous and abnormal vascularity. Subtypes of vascular habitats within the tumor and edema can be distinguished: high angiogenic tumor (HAT), low angiogenic tumor (LAT), infiltrated peripheral edema (IPE), and vasogenic peripheral edema (VPE).

Purpose: To validate the association between hemodynamic markers from vascular habitats and overall survival (OS) in glioblastoma patients, considering the intercenter variability of acquisition protocols.

View Article and Find Full Text PDF

The current criteria for diagnosing Alzheimer's disease (AD) require the presence of relevant cognitive deficits, so the underlying neuropathological damage is important by the time the diagnosis is made. Therefore, the evaluation of new biomarkers to detect AD in its early stages has become one of the main research focuses. The purpose of the present study was to evaluate a set of texture parameters as potential biomarkers of the disease.

View Article and Find Full Text PDF

Objectives: Vascular characteristics of tumour and peritumoral volumes of high-grade gliomas change with treatment. This work evaluates the variations of T2*-weighted perfusion parameters as overall survival (OS) predictors.

Methods: Forty-five patients with histologically confirmed high-grade astrocytoma (8 grade III and 37 grade IV) were included.

View Article and Find Full Text PDF