Very low-molecular-mass fragments of albumin in the plasma of patients with focal segmental glomerulosclerosis.

Background: Primary focal segmental glomerulosclerosis (FSGS) is a glomerular disease that frequently does not respond to treatment and progresses to kidney failure. FSGS can be of either genetic origin, caused by mutations in slit diaphragm proteins, such as podocin, or idiopathic origin of unknown cause.

Study Design: Case series.