Accuracy of auditory steady state and auditory brainstem responses to detect the preventive effect of polyphenols on age-related hearing loss in Sprague-Dawley rats.

Aging causes histological, electrophysiological and molecular changes in the cochlea. The free radical theory of aging, has obtained consensus, and the mitochondrion is reported to play a key role in aging as a major source of reactive oxygen species. In the last years, there has been a significant increase in the interest in polyphenols because of the antioxidant properties and their role in the prevention of various diseases associated with oxidative stress, including aging.

Utility of auditory steady-state and brainstem responses in age-related hearing loss in rats.

Conclusions: The results support the idea that auditory steady-state response (ASSR) is a more accurate test for studying age-related hearing loss (ARHL) in Sprague-Dawley rats. Differences in the rat middle ear may explain the variations of the click properties, with a displacement of the energy toward the 8 and 10 kHz frequencies compared with humans.

Objectives: The purpose of this study was to evaluate ARHL in older and younger Sprague-Dawley rats using auditory clicks and tone burst with auditory brainstem response (ABR), in addition to ASSR.

[Peripheral facial palsy. Descriptive study at the university hospital in Getafe].

Objective: Our aim is to validate a protocol for the diagnosis and treatment of peripheral facial palsy.

Material And Method: A cross-sectional and retrospective descriptive study was made of 63 patients diagnosed with facial palsy and given out-patient follow-up care.

Results: The average age was 41 years, with a 60 % preponderance of men, and the predominant side was the left one with a House-Brackmann degree of III on debut.