Publications by authors named "Enrique A Hernandez-Bustamante"

Article Synopsis
  • * A meta-analysis of 28 studies, with a total of 29,195 participants, revealed an overall prevalence of 30.3%, with variation based on altitude levels.
  • * Key findings show that women had a higher prevalence (35.5%) than men (26.8%), and the disease components like abdominal obesity and low HDL cholesterol were notably common, while high blood pressure and high triglycerides were less frequent.
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Background: Some studies have reported that homocysteine, vitamin B12, and folic acid levels are associated with polycystic ovary syndrome (PCOS), whereas other studies yielded controversial results.

Objectives: This study aimed to systematize the available evidence of homocysteine, vitamin B12, and folate levels in women with and without PCOS.

Design: Systematic review and meta-analysis.

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  • This study reviews existing research on asprosin levels in patients with type 2 diabetes (T2D), metabolic syndrome (MetS), and obesity to explore its potential as a treatment for metabolic-endocrine disorders.
  • A systematic analysis of 26 studies found that individuals with T2D, MetS, and obesity had significantly higher asprosin levels compared to those without these conditions.
  • The results suggest that asprosin could serve as a biomarker for metabolic disorders, as its levels are notably elevated in T2D, MetS, and obesity patients.
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  • * A systematic literature review analyzed 1359 articles, identifying 33 valid studies involving 96,909 animals, finding a pooled prevalence of 5.0% in birds, 1.0% in pigs, and 0.0% in cats and dogs.
  • * Although H5N1 appears less common in animals compared to other influenza strains, its potential to cause severe illness in humans underscores the importance of monitoring its prevalence and understanding contributing factors for effective prevention.
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Introduction: Dengue is a vector-borne disease, especially important in tropical and subtropical areas. The first presentation of many arboviral diseases occurred mainly in animals, including multiple and , such as dengue.

Objective: To determine the serological and molecular frequency of the dengue virus in animals.

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  • Mpox, a zoonotic disease that became widespread in 2022, lacks comprehensive reviews on its occurrence in animals, prompting a systematic review and meta-analysis to determine its prevalence.
  • The study evaluated 15 reports and revealed a pooled prevalence of 16.0% in non-human primates, 8.0% in rodents, and 1.0% in shrews based on molecular or serological tests conducted on 2,680 animals.
  • The research highlights the need for further studies in various animal species to understand Mpox's natural infection rates and stresses the importance of a OneHealth approach for effective public health strategies.
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  • A study highlights the prevalence of medicinal plant consumption among Peruvians for preventing COVID-19, with 60% of participants using them, especially in the Peruvian highlands and among those with personal ties to COVID-19 cases.* -
  • Most participants (84.6%) were young adults, and key factors driving this consumption included family experiences with COVID-19, perceptions of increased infection risk, and reliance on medical information regarding COVID-19.* -
  • The findings stress the need for communication strategies to educate the public on the risks associated with medicinal plants and promote validated preventive measures against COVID-19.*
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Objective: We aimed to review the available evidence on the association between vitamin B12, folate, and homocysteine levels with worse outcomes among COVID-19 patients.

Methods: The search was carried out in ten databases simultaneously run on 10 May 2023, without language restrictions. We included cross-sectional, case-control, and cohort studies.

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Background And Aims: The presence of fungal infections has been described in patients after recovering from COVID-19. This study aims to conduct a systematic review of studies that reported fungal infections ( spp., , or spp.

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Snakebites still constitute a significant public health problem in developing countries and are considered a neglected tropical condition by the WHO. Snake accidents are associated with substantial morbidity and mortality and may produce secondary complications, such as severe infections. The objective of this systematic review was to determine the prevalence of snakebite infections and characterize the bacteria isolated from these infections.

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We summarize the clinical trials (CTs) main characteristics, including members of ethnic minorities from Latin America. We carried out a systematic search in six databases. We made a descriptive synthesis of CTs, summarizing the characteristics, interventions, main findings, results, and conclusions reported.

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Background & Aims: Metabolic syndrome (MetS) is associated with life-threatening conditions. Several studies have reported an association of vitamin B12, folic acid, or homocysteine (Hcy) levels with MetS. This systematic review and meta-analysis assessed the association of vitamin B12, folic acid, and Hcy levels with MetS.

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Aim: Low- and middle-income countries represent nearly 85% of all cervical cancer cases worldwide; thereby, it is extremely important to identify methods to improve the screening process. Therefore, this study aimed to summarize the primary characteristics of studies on accessibility, coverage, patient preferences, and factors associated with patient satisfaction or acceptance of colposcopy in primary healthcare.

Methods: A search strategy, based on MeSH, Emtree, and free terms, was run through 5 databases (PubMed, Scopus, Embase, Ovid/Medline, and Web of Science).

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  • Toxocariasis is a parasitic infection affecting canines, felines, humans, and other vertebrates, primarily acquired through embryonated eggs found in the environment, posing health risks for humans and animals, particularly in park settings.
  • A systematic review and meta-analysis of 49 studies revealed that the pooled prevalence of Toxocara spp. eggs in Latin American parks is 50.0%, with Argentina showing the highest rate at 100%.
  • The findings highlight a significant public health concern, especially for children who play in contaminated areas, emphasizing the need for better awareness and preventative measures among pet owners and the public.
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Introduction: Bovine brucellosis is a significant public health problem in countries with economic and zoonotic implications. Although relevant, there are no previous systematic reviews about bovine brucellosis in Latin America.

Methods: We performed a systematic literature review in five data-bases to assess the seroprevalence of Brucella in cattle.

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Article Synopsis
  • - The study aimed to analyze and summarize data about the prevalence of human toxocariasis in Latin America and the Caribbean by examining 101 articles that included over 31,000 participants.
  • - The overall seroprevalence of toxocariasis was found to be 31.0%, with notable findings indicating higher rates among pet owners and lower rates in adult-only populations.
  • - The research highlights the need for improved epidemiological surveillance strategies to prevent and identify toxocariasis, as the disease is significant in areas with high prevalence.
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Background & Aims: Apolipoproteins and lipoprotein(a) are associated with various cardiometabolic diseases, including insulin resistance, diabetes mellitus, hypertension, dyslipidemia, among others. This systematic review and meta-analysis was conducted to evaluate the association of these markers with metabolic syndrome (MetS).

Methods: We ran a systematic search through PubMed, Scopus, Embase, Ovid/Medline, and Web of Science on March 15, 2023.

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Background And Aims: Numerous studies have found an association between vitamin deficiency and thyroid disorders (TD). The presence of anti-parietal cell antibodies is indicative of reduced ability to absorb vitamin B12. Thus, this study reviewed the existing studies with the objective of assessing differences in the serum levels of vitamin B12 among patients with and without TD, the frequency of vitamin B12 deficiency in patients with TD, and the presence of anti-parietal cell antibodies in patients with TD.

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The systemic immune-inflammation index (SIII) is a marker studied in multiple types of urologic cancer. This systematic review evaluates the association between SIII values with overall survival (OS) and progression-free survival (PFS) in testicular cancer. We searched observational studies in five databases.

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Article Synopsis
  • Rickettsioses are microorganisms that can be transmitted to both animals and humans, but their prevalence in horses hasn't been thoroughly studied until recently.
  • A systematic review assessed horse infections using five databases, revealing a pooled prevalence of 37.0% with significant variation among studies.
  • The analysis found varying prevalence rates based on testing methods, with implications for human health due to potential zoonotic transmission from horses and their ticks, highlighting the risk of disease spillover.
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Various studies suggest that the atherogenic index of plasma (AIP) is associated with the risk of coronary artery disease (CAD) in different clinical scenarios. This review aimed to synthesize evidence of the association between AIP values and CAD. A literature search was carried out on four databases, namely, PubMed, Scopus, Web of Science, and Ovid-Medline.

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Vaccination it is considered a vital strategy in order to mitigate monkeypox by protecting from severe disease and helping in reduction of hospitalisations. In this sense, this study aims to estimate the global prevalence of vaccination acceptance against monkeypox. We conducted a systematic review with a comprehensive search strategy for the following databases: PubMed, Scopus and Web of Science.

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Lymphocyte-to-Monocyte ratio (LMR) has shown an association with survival outcomes in several oncological diseases. This study aimed to evaluate the association between LMR and clinical outcomes for cholangiocarcinoma patients. A systematic review and meta-analysis were performed to assess the association between LMR values and overall survival (OS), disease-free survival (DFS), recurrence-free survival (RFS) and time to recurrence (TTR) in cholangiocarcinoma patients.

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Background And Aims: Biomarkers are necessary to stratify the risk of diabetic foot ulcers (DFUs). This systematic review and meta-analysis aimed to evaluate the association between the lipid profile and apolipoproteins with the risk of DFU.

Methods: A systematic search was conducted in PubMed, Scopus, Cochrane Library, and Web of Science among adult patients.

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C-reactive protein-to-albumin ratio (CAR) is an independent risk factor in cardiovascular, cerebrovascular, and infectious diseases. Through this study, we investigated the CAR values with respect to the severity and mortality of COVID-19 patients. We performed a systematic review and meta-analysis to retrieve studies that evaluated CAR values upon hospital admission in relation to the severity or mortality of COVID-19 patients.

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