Publications by authors named "Enrico Ruffino"

Article Synopsis
  • This study aimed to evaluate the safety and feasibility of starting sacubitril/valsartan therapy in patients with acute decompensated heart failure after they were stabilized in the hospital.
  • Conducted over five years in two Italian medical centers, the study tracked patient outcomes, focusing on how many were discharged on the medication and any adverse events during and after hospitalization.
  • Results showed that 91% of the 122 patients were discharged on sacubitril/valsartan, indicating that starting this treatment during hospitalization is both safe and practical for most patients.
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Background: Few studies prospectively assessed risk factors for ventricular fibrillation (VF) during a first myocardial infarction (MI). We designed a nation-wide study aiming to identify clinical and genetic characteristics associated with primary VF; and report here about clinical features.

Methods: PREDESTINATION (PRimary vEntricular fibrillation and suDden dEath during a firST myocardIal iNfArcTION) is an Italian case-control, prospective multicentre study.

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Background: Syncope is considered a risk factor for life-threatening arrhythmias in Brugada patients. Distinguishing a benign syncope from one due to ventricular arrhythmias is often difficult, unless an ECG is recorded during the episode. Aim of the study was to analyze the characteristics of syncopal episodes in a large population of Brugada patients and evaluate the role of electrophysiological study (EPS) and the prognosis in the different subgroups.

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