Publications by authors named "Enrico Mario Camporesi"

Carbon Monoxide (CO) intoxication is still a leading cause of mortality and morbidity in many countries. Due to the problematic detection in the environment and subtle symptoms, CO intoxication usually goes unrecognized, and both normobaric and hyperbaric oxygen (HBO) treatments are frequently administered with delay. Current knowledge is mainly focused on acute intoxication, while Delayed Neurological Sequelae (DNS) are neglected, especially their treatment.

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A patient suffered from an envenomation that, at his hospitalization, was judged severe: Grade 3 out of 3, as defined in clinical studies for CroFab™ antidote [Crotalidae Polyvalent Immune Fab (Ovine)]. In addition to the usual antivenom treatment we applied adjunctive hyperbaric oxygen (HBO₂) therapy. Our aim was to facilitate better control of the lesions, already presenting as problematic wounds and at high risk of necrotizing soft tissue infection with compartment aspects.

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Article Synopsis
  • Hyperbaric Oxygen (HBO) therapy is a treatment method using pure oxygen in a pressurized environment, shown to help with various infections, especially those caused by multidrug-resistant microorganisms.
  • The study aimed to explore how increased oxygen pressure (pO2) affects certain bacteria, using four specific experimental setups to measure changes in microbial resistance after hyperbaric treatment.
  • Results indicated that HBO can have bactericidal effects when pressure is elevated, though the effectiveness is not solely dependent on oxygen levels, and combining HBO with antibiotics can enhance the treatment of resistant bacteria.
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