Publications by authors named "Enrico Fruttero"

Article Synopsis
  • Recent advancements in stage III melanoma treatment focus on adjuvant therapies, leading to a decrease in completion lymph node dissection (CLND) procedures after positive sentinel node biopsy (SLNB).
  • A study from the University of Turin compared relapse-free survival (RFS) and overall survival (OS) in 157 melanoma patients, finding no significant difference between those who underwent CLND and those who did not.
  • The findings suggest that while CLND has minimal impact on RFS or OS, adjuvant therapies significantly lower the risk of relapse, highlighting their importance in treating melanoma patients.
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Introduction: Surgery represents the primary treatment option for cutaneous squamous cell carcinoma (cSCC) aiming for complete tumor resection (R0). Recurrence and metastasis significantly affect survival and outcomes, and poorly differentiated (G3) cSCC is associated with a higher risk of recurrence. However, the specific clinical and histopathological features that predict recurrence and progression in G3-cSCC remain unclear.

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Purpose: This study evaluated the characteristics of patients with head and neck (H&N) melanoma who underwent sentinel lymph node biopsy (SNLB) and assessed the clinical course of patients categorizing subjects according to SLNB status and melanoma location (scalp area vs. non-scalp areas). Methods: Patients undergoing SLNB for melanoma of H&N from 2015 to 2021 were prospectively characterized according to sentinel lymph node (SLN) status.

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