Biodegradability of dietary supplements: Advanced analytical methods to study the environmental fate of artificial sweeteners and dyes.

Artificial sweeteners (ASs) and dyes are widely used in foods, beverages and pharmaceutical and are recognized as emerging environmental contaminants due to their persistence and widespread occurrence. These substances often pass through the human body unchanged and resist wastewater treatment processes, leading to continuous introduction into aquatic environments and potential long-lasting term environmental effects. This study investigated, for the first time, the biodegradability of nine commercial dietary supplements, both natural and those containing ASs and synthetic dyes, using the Organisation for Economic Cooperation and Development (OECD) 301 F ready biodegradation test (RBT), which is a respirometry-manometric method.

Metabolomic fingerprint of Hamamelis virginiana L. gallotannins by suspect screening analysis with UHPLC-qToF and their semiquantitative evaluation.

The evolution of the regulatory framework for medical devices in the EU (Reg 2017/745) has opened the study of complex systems emerging properties. This makes necessary to identify new analytical approaches able of characterizing complex natural substrates as completely as possible. Therefore, omics approaches and advanced analytical methods for the determination of metabolite classes appear to be at the forefront to meet this need.

Intra-Articular Route for the System of Molecules 14G1862 from : Pain Relieving and Protective Effects in a Rat Model of Osteoarthritis.

Current pharmacological therapies for the management of chronic articular diseases are far from being satisfactory, so new strategies need to be investigated. We tested the intra-articular pain relieving properties of a system of molecules from a characterized extract (14G1862) in a rat model of osteoarthritis induced by monoiodoacetate (MIA). 14G1862 (0.

Method for studying the effects of thermal deformations on optical systems for space application.

In this paper, the results of the thermo-elastic analysis performed on the stereo channel of the imaging system Integrated Observatory System for the BepiColombo European Space Agency mission to Mercury are presented. The aim of the work is to determine the effects of ambient parameter variations on the equipment performance; the optical performance is changing during the mission lifetime primarily because of the optics misalignments and deformations induced by temperature variations. The camera optics and their mountings are modeled and processed by a thermo-mechanical finite element model (FEM) program, which reproduces the expected optics and structure thermo-elastic deformations in the instrument foreseen operative temperature range, i.

Accumulation and erosion of Mars' south polar layered deposits.

Mars' polar regions are covered with ice-rich layered deposits that potentially contain a record of climate variations. The sounding radar SHARAD on the Mars Reconnaissance Orbiter mapped detailed subsurface stratigraphy in the Promethei Lingula region of the south polar plateau, Planum Australe. Radar reflections interpreted as layers are correlated across adjacent orbits and are continuous for up to 150 kilometers along spacecraft orbital tracks.