Publications by authors named "Enrico Dumbra Bonini"
Cancers (Basel)
October 2021
Article Synopsis
- Breast cancer (BC) is a leading cause of mortality among women, and female dogs are effective models for studying the disease.
- The study examined the use of liquid biopsy to detect gene mutations in BC diagnosis and monitoring, involving 57 women and 37 female dogs, with DNA and ctDNA analyzed through next-generation sequencing.
- Results showed a significant number of variants in both species, with specific genes linked to tumor recurrence, indicating that liquid biopsy can aid in identifying genetic changes at the onset of BC and throughout treatment.
