Publications by authors named "Enrico Bautista"
Pharmaceuticals (Basel)
March 2024
Article Synopsis
- Current methods for selecting epitopes for peptide vaccines often focus on binding affinity, highlighting the need for better in silico tools to identify immunologically significant epitopes.
- AutoPepVax is a new software designed to streamline epitope selection by identifying safe and effective epitopes that can potentially stimulate immune responses, utilizing advanced machine learning techniques.
- The program was used to create a pan-cancer peptide vaccine targeting common mutations in the epidermal growth factor receptor (EGFR), showing promise with a high population coverage for the selected epitopes across different cancer types.
