Background: There is enough evidence to support the knowledge that multicentric reticulohistiocytosis (MR) is a histiocytic proliferative disorder; however, the type of histiocytes involved is not well established.
Objective And Methods: To study the nature of cells present in MR lesions by studying the immunohistochemical profile of three new cases and reviewing 23 cases reported in the literature.
Results: MR histiocytic cells are positive for vimentin, CD68, and CD45, negative for S-100 protein, CD34, and XIIIa factor, and weak reactors for thrombomodulin.
Purpose: To describe an unusual case of disseminated sporotrichosis with intraocular involvement.
Design: Interventional case report.
Results: An 18-year-old man presented with disseminated ulcerated skin lesions.