Exhaled breath condensate markers of oxidative stress in male storekeepers of chemical stores in the Ariaria international market Aba Abia state Nigeria.

In most developing countries, stores, where chemical substances are sold, are poorly ventilated, and best practices are not followed. This can result in the contamination of the ambient air inside the stores with toxicological implications for the lungs. This work aimed at determining the risk of pulmonary disease in chemical storekeepers in the Ariaria international market Aba by the evaluation of exhaled breath condensate (EBC) biomarkers of oxidative stress.

Hepato-renal toxicities associated with heavy metal contamination of water sources among residents of an oil contaminated area in Nigeria.

Objectives: This study was conducted to estimate the heavy metal (HM) content of water sources from oil contaminated area, HM and hepato-renal functions of residents and to determine association between consumption of crude oil contaminated water and development of multiple organ toxicities.

Methods: Heavy metals (Pb, Cd, As, Hg) content of 20 surface water sources (SWS) and 20 underground water sources (UWS) from crude oil contaminated area and 40 water sources (20 SWS and 20 UWS) from uncontaminated area (controls) were estimated using AAS. The HM, indices of liver function (aspartate and alanine aminotransferases (AST and ALT), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), total protein (TP), albumin, total and conjugated bilirubin (TB and CB)) and renal functions (urea, creatinine, sodium, chloride, potassium, bicarbonate and kidney injury molecule-1 (KIM-1)) were determined in 120 residents each from contaminated and control areas using enzyme-colorimetry and ELISA methods.