A patient with 18p11.32-p11.21 deletion have monaural deafness caused by an inadequate haplodose of THOC1: A case report.

Background: THOC1 mutation causes Deafness, autosomal dominant 86 [OMIM: 620280]. However, it has not been reported whether deletion of the THOC1 gene causes deafness.

Methods: Here, we report a 1-year-old girl with clinical features including Hypotonia, unilateral deafness in the right ear, and widening of lateral ventricles in 6 months.

[Clinical study on the treatment of juvenile recurrent laryngeal papilloma].

Objective: To study and evaluate the feasibility and effect of the treatment for juvenile recurrent laryngeal papilloma by nasal endoscopy electric suction cutting and laser surgery.

Method: The clinical data of 26 cases with juvenile recurrent laryngeal papilloma from 2002-2007 years were retrospectively analyzed. Six cases were treated by electric suction cutting under nasal endoscopy, 20 cases were treated by electric suction cutting under nasal endoscopy and synergizing laser, and postoperative wound with sodium hyaluronate gel treatment.