Fertility Fails to Predict Voter Preference for the 2020 Election: A Pre-Registered Replication of Navarrete et al. (2010).

As part of the Systematizing Confidence in Open Research and Evidence (SCORE) program, the present study reassesses the claim made in Navarrete et al. (2010) Study 1, that women's voter preference for male candidates who demonstrate cues of strong genetic fitness increases across the reproductive cycle as a function of conception risk. We report an attempt to conceptually replicate these findings, modifying the outcome variables for voter preference to reflect the 2020 election rather than the 2008 election, while maintaining fidelity to the original study by including Barack Obama as a candidate.

Dataset for the characterisation of thermal stratification in horizontally configured electric water heaters.

A test station was designed and built to measure the thermal stratification (vertical thermal gradients) in a horizontal 150 L electric water heater storage device for different external environmental and user-emulating inputs, ambient temperature, inlet water temperature, water draw flow rate, thermostat temperature and heating coil active time. Stratification measurement consists of 66 temperature sensors that coarsely map three-dimensional temperature gradients within the horizontally configured heating device, under different operational conditions. Other significant temperatures such as inlet, outlet, ambient, thermostat feedback, and wall temperatures were also recorded.

On mathematical modeling of the propagation of a wave ensemble within an individual axon.

The long history of studying the propagation of an action potential has revealed that an electrical signal is accompanied by mechanical and thermal effects. All these effects together generate an ensemble of waves. The consistent models of such a complex phenomenon can be derived by using properly the fundamental physical principles.

Distribution, causal agents, and infection dynamic of emerging ink disease of sweet chestnut in Southern Switzerland.

Emerging diseases caused by both native and exotic pathogens represent a main threat to forest ecosystems worldwide. The two invasive soilborne pathogens Phytophthora cinnamomi and Phytophthora × cambivora are the causal agents of ink disease, which has been threatening Castanea sativa in Europe for several centuries and seems to be re-emerging in recent years. Here, we investigated the distribution, causal agents, and infection dynamics of ink disease in southern Switzerland.

Will we ever teach mathematics again in the way we used to before the pandemic?

After about two years of emergency remote teaching during the pandemic, the teaching of mathematics is slowly returning to (what used to be called) . However, after the period of mostly teaching online, there is uncertainty about the extent to which we will return to the way we were teaching before. In this survey paper we attempt to give some background to the impact that emergency remote teaching may have had on teaching mathematics.

The impact of COVID-19 on the format and nature of academic conferences in mathematics education.

The global COVID-19 pandemic has provided an opportunity to re-examine the possibility of organising virtual conferences in mathematics education, in which the social needs of participants can also be addressed. In this study we investigated the future impact that this change may have on the format and nature of mathematics education conferences. The study was conducted in two phases.

Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial.

Background: Vilobelimab, an anti-C5a monoclonal antibody, was shown to be safe in a phase 2 trial of invasively mechanically ventilated patients with COVID-19. Here, we aimed to determine whether vilobelimab in addition to standard of care improves survival outcomes in this patient population.

Methods: This randomised, double-blind, placebo-controlled, multicentre phase 3 trial was performed at 46 hospitals in the Netherlands, Germany, France, Belgium, Russia, Brazil, Peru, Mexico, and South Africa.

Using enaction to evolve from pre-Covid to post-Covid pedagogy: a case study with South African mathematics teachers.

The Covid-19 pandemic and subsequent national lockdown in South Africa induced a rapid, albeit challenging, implementation of blended learning (with a strong online focus) at all educational levels. During this time, a group of teachers were involved in a specialised computer integrated education course, preparing them for the design and implementation of technologically enhanced modes of teaching. In this research we considered the positive impact of the situation during the pandemic on these mathematics teachers' practice, as well as their conceptualisation of the way forward for technology enhanced mathematics education.

Differing Responses to Infection in Susceptible and Partially Resistant (Mill.) Rootstocks: A Case for the Role of Receptor-Like Kinases and Apoplastic Proteases.

The hemibiotrophic plant pathogen Rands is the most devastating pathogen of avocado ( Mill.) and, as such, causes significant annual losses in the industry. Although the molecular basis of resistance in avocado and virulence determinants have been the subject of recent research, none have yet attempted to compare the transcriptomic responses of both pathogen and host during their interaction.

Mechanical waves in myelinated axons.

The propagation of an action potential in nerves is accompanied by mechanical and thermal effects. Several mathematical models explain the deformation of the unmyelinated axon wall (a mechanical wave). In this paper, the deformation of the myelinated axon wall is studied.

The Identification and Characterization of Endopolygalacturonases in a South African Isolate of .

is an economically important plant pathogen that has caused devastating losses to the avocado industry worldwide. To facilitate penetration and successful colonization of the host plant, pathogens have been reported to secrete polygalacturonases (PGs). Although a large PG gene family has been reported in , in-depth bioinformatics analyses and characterization of these genes is still lacking.

Partially Resistant Avocado Rootstock Dusa Shows Prolonged Upregulation of Genes in Response to Infection.

Avocado is an important agricultural food crop in many countries worldwide. , a hemibiotrophic oomycete, remains one of the most devastating pathogens within the avocado industry, as it is near impossible to eradicate from areas where the pathogen is present. A key aspect to Phytophthora root rot disease management is the use of avocado rootstocks partially resistant to , which demonstrates an increased immune response following infection.

Population Genetic Analyses of Reveals Three Lineages and Movement Between Natural Vegetation and Avocado Orchards in South Africa.

is the causal agent of root rot, canker, and dieback of thousands of plant species around the globe. This oomycete not only causes severe economic losses to forestry and agricultural industries, but also threatens the health of various plants in natural ecosystems. In this study, 380 isolates of from four avocado production areas and two regions of natural vegetation in South Africa were investigated using 15 microsatellite markers.

Expression of several Phytophthora cinnamomi putative RxLRs provides evidence for virulence roles in avocado.

Phytophthora cinnamomi is a plant pathogenic oomycete that causes Phytophthora root rot of avocado (PRR). Currently, there is a limited understanding of the molecular interactions underlying this disease. Other Phytophthora species employ an arsenal of effector proteins to manipulate host physiology, of which the RxLR effectors contribute to virulence by interfering with host immune responses.

Stereotypy and spontaneous alternation in deer mice and its response to anti-adenosinergic intervention.

Repetitive behavioral phenotypes are a trait of several neuropsychiatric disorders, including obsessive-compulsive disorder (OCD). Such behaviors are typified by complex interactions between cognitive and neurobiological processes which most likely contribute to the suboptimal treatment responses often observed. To this end, exploration of the adenosinergic system may be useful, since adenosine-receptor modulation has previously shown promise to restore control over voluntary behavior and improve cognition in patients presenting with motor repetition.

Development of a Competency Model for Placement and Verification of Nasogastric and Nasoenteric Feeding Tubes for Adult Hospitalized Patients.

Nasogastric/nasoenteric (NG/NE) feeding tube placements are associated with adverse events and, without proper training, can lead to devastating and significant patient harm related to misplacement. Safe feeding tube placement practices and verification are critical. There are many procedures and techniques for placement and verification; this paper provides an overview and update of techniques to guide practitioners in making clinical decisions.

Genome of the destructive oomycete Phytophthora cinnamomi provides insights into its pathogenicity and adaptive potential.

Background: Phytophthora cinnamomi is an oomycete pathogen of global relevance. It is considered as one of the most invasive species, which has caused irreversible damage to natural ecosystems and horticultural crops. There is currently a lack of a high-quality reference genome for this species despite several attempts that have been made towards sequencing its genome.

Advances in Understanding Defense Mechanisms in Against .

Avocado () is an economically important fruit crop world-wide, the production of which is challenged by notable root pathogens such as and . Arguably the most prevalent, , is a hemibiotrophic oomycete which causes Phytophthora root rot, leading to reduced yields and eventual tree death. Despite its' importance, the development of molecular tools and resources have been historically limited, prohibiting significant progress toward understanding this important host-pathogen interaction.

Psychobehavioral Treatment Options for Sexual Dysfunction in Multiple Sclerosis: A Systematic Review.

Background: Sexual dysfunction in multiple sclerosis (MS) is a significant but overlooked impairment, and treatment options are rare. The aims of this systematic review were to identify psychological interventions used to treat sexual dysfunction in MS, to estimate their benefit, and to note appropriate treatment approaches for research projects and clinical use.

Methods: A systematic review update was conducted to find psychological interventions aiming to improve sexual dysfunction in MS.

Transformation of the mathematics classroom with the internet.

Growing use of the internet in educational contexts has been prominent in recent years. In this survey paper, we describe how the internet is transforming the mathematics classroom and mathematics teacher education. We use as references several reviews of use of the internet in mathematics education settings made in recent years to determine how the field has evolved.

Modelling of processes in nerve fibres at the interface of physiology and mathematics.

The in silico simulations are widely used in contemporary systems biology including the analysis of nerve pulse propagation. As known from numerous experiments, the propagation of an action potential is accompanied by mechanical and thermal effects. This calls for an analysis at the interface of physics, physiology and mathematics.