Publications by authors named "Endika Martinez-Gutierrez"
Background: Multiple Organ failure (MOF) is one of the main causes of admission to the Intensive Care Unit (ICU) of patients infected with COVID-19 and can cause short- and long-term neurological deficits.
Objective: To compare the cognitive functioning and functional brain connectivity at 6-12 months after discharge in two groups of individuals with MOF, one due to COVID-19 and the other due to another cause (MOF-group), with a group of Healthy Controls (HC).
Methods: Thirty-six participants, 12 from each group, underwent a neuropsychological and neuroimaging assessment at both time-points.
Article Synopsis
- Different brain regions display shared statistical dependencies during tasks and rest, reflecting functional connections; however, negatively correlated networks (anticorrelated networks - ACNs) have been less studied than positively correlated ones.
- The study utilized three neuroimaging datasets to identify and compare ACNs across healthy young adults, older participants, and among a larger sample for cognitive associations, highlighting distinct resting-state networks and ranking key brain areas involved.
- Key findings indicate increased anticorrelation in cerebellar interactions among older subjects, as well as unique clusters in cognitive score associations, signifying the functional relevance of ACNs in understanding brain activity and potential alterations in various conditions.
Article Synopsis
- The study aimed to create a device that identifies pain perception by analyzing the brain's electrical activity and blood flow while applying heat stimuli to participants.
- A prototype was tested on 35 healthy subjects, measuring their heat pain thresholds and comparing their responses under painful and non-painful conditions through EEG and PPG signals.
- Results showed that specific changes in spectral entropy from EEG and PPG could distinguish between pain and no pain, indicating potential applications for monitoring pain in various neurological conditions.