Time to recovery and its predictors among neonates undergone phototherapy at Comprehensive Specialized hospitals of the Northwest Ethiopia.

Phototherapy is the preferred treatment for neonatal hyperbilirubinemia and has largely replaced exchange transfusions due to its effectiveness and safety. The primary aim of this study was to evaluate the time to recovery and its predictors among neonates undergoing phototherapy at the Neonatal Intensive Care Unit of the Northwest Comprehensive Specialized Hospital in Northwest Ethiopia. A multi-center institution-based retrospective follow-up study was conducted among 423 neonates admitted to the neonatal intensive care unit between September 2019 and December 2023, at Comprehensive Specialized Hospitals of Northwest Ethiopia.

Incidence and predictors of acute kidney injury among asphyxiated neonates in comprehensive specialized hospitals, northwest Ethiopia, 2023.

Acute kidney injury (AKI) is characterized by a sudden decline in the kidneys' abilities to remove waste products and maintain water and electrolyte homeostasis. This study aims to determine the incidence and predictors of acute kidney injury among neonates with perinatal asphyxia admitted at the neonatal intensive care unit of West Amhara Comprehensive Specialized Hospital, Northwest Ethiopia, 2023. Multicentred institution-based retrospective follow-up study was conducted from October 1, 2021, to September 30, 2023, among 421 perinatal asphyxia neonates.

Time to death and its predictors among neonates admitted with sepsis in neonatal intensive care unit at comprehensive specialized hospitals in Northeast Ethiopia.

Background: In impoverished nations like Ethiopia, neonatal sepsis contributes significantly to neonatal mortality. Despite variations in the specific timing of death and predictors of neonatal mortality associated with sepsis across different settings, there's limited documented information in the Neonatal Intensive Care Units of northeastern Ethiopia. Consequently, the aim of this study was to determine time to death and its predictors among neonates with sepsis admitted to Neonatal Intensive Care Units in comprehensive specialized hospitals in northeastern Ethiopia.

Advanced age, comorbidity and the risk of mortality in COVID-19 infection.

Background: Advanced age and comorbidities have been described to increase the risk of mortality associated with COVID-19 infection. However, the degree to which comorbidities influence mortality among younger and older adults with and without comorbidity in COVID-19 infection has not been clearly elucidated.

Objective: To examine the impact of comorbidity on mortality among younger and older unvaccinated adults with COVID-19 infection admitted to a safety-net hospital.

Association Between Physical Exercise and Cognitive Function Among Community-Dwelling Older Adults.

Objectives: To examine the association between self-reported physical exercise and cognitive function.

Design: Secondary data analysis of a prospective cohort study.

Participants: Community-dwelling older adults with normal cognitive function at baseline.

Self-reported insomnia symptom, sleep duration and the risk of recurrent falls among older men and women.

Background/objectives: Previous studies have reported conflicting results on the association between sleep disturbance and recurrent falls. The objective of the current study was to examine the risk of recurrent falls among community-dwelling older adults who reported one or more insomnia symptoms along with normal, short and long sleep durations in comparison with those who reported no insomnia symptom and normal sleep duration.

Design: Secondary data analysis of a prospective cohort study.

Organized Social Activity, Physical Exercise, and the Risk of Insomnia Symptoms Among Community-Dwelling Older Adults.

To compare the risk of insomnia symptoms among community-dwelling older adults who participated and did not participate in organized social activity and physical exercise. Secondary data analysis of a prospective cohort study. Community-dwelling older adults ≥65 years of age with no insomnia symptoms at baseline were included in the study.

Nocturia, Insomnia Symptoms and Mortality among Older Men: The Health, Aging and Body Composition Study.

Study Objectives: To examine the association between nocturia (walking up from sleep for urination) and mortality risk among community dwelling older men.

Methods: This is a secondary data analysis using data obtained from the Health Aging Body Composition (Health ABC) study. Frequency of nocturia was determined at baseline using a questionnaire.

Association Between Social and Physical Activities and Insomnia Symptoms Among Community-Dwelling Older Adults.

Objective: To examine the association between organized social activity, walking exercise, and insomnia symptoms.

Material And Method: Data for analysis are derived from the National Health Aging Trends Study (NHATS). At baseline, demographic characteristics, socioeconomic status, health-related behaviors, sleep-related problems, and health status were assessed using questionnaires.

Do sleep complaints predict persistent fatigue in older adults?

Objectives: To examine the association between sleep complaints, use of sleep-promoting medications, and persistent severe fatigue (PSF).

Design: Analysis of data from the National Health Aging Trends Study.

Setting: Contiguous United States.

Snoring, daytime sleepiness, and incident cardiovascular disease in the health, aging, and body composition study.

Objectives: To examine the association between snoring and incident cardiovascular disease (CVD).

Design Settings And Participants: This is a prospective study in which community dwelling older adults were evaluated at baseline, and followed up for an average of 9.9 years.

Association between sleep and breast cancer incidence among postmenopausal women in the Women's Health Initiative.

Study Objectives: To determine whether the duration of sleep, sleep quality, insomnia, or sleep disturbance was associated with incident breast cancer in the Women's Health Initiative (WHI).

Design: Prospective cohort study.

Setting: Women enrolled in one of the Clinical Trial (CT) arms or the Observational Study (OS) from the WHI conducted in the United States.

Self-rated sleep characteristics and bother from nocturia.

Purpose: The aim of this study was to evaluate if men with varying degrees of bother from a similar number of nocturia episodes differ with respect to self-rated sleep characteristics and fatigue.

Materials And Methods: As part of the baseline assessments during a nocturia treatment trial, 55 participants reported frequency and bother of nocturia using the AUA Symptom Inventory and completed 7-day sleep diaries prior to treatment. Participants who reported moderate nocturia (either two or three episodes nightly) were further grouped into categories of LOW (nocturia is no problem or a very small problem) or HIGH bother (nocturia is a big problem).

Sleep-disordered breathing and frailty in the Cardiovascular Health Study Cohort.

Sleep-disordered breathing (SDB) is associated with pathophysiology that may influence the development and progression of frailty. Using data collected in 1995-1996, the authors explored the relation between SDB and components of frailty among 1,042 participants of the Cardiovascular Health Study. Diagnosis of SDB was based on the results of overnight polysomnography, and severe SDB was defined as an apnea-hypopnea index of >30 per hour of sleep.

A multicomponent behavioural and drug intervention for nocturia in elderly men: rationale and pilot results.

OBJECTIVES To evaluate the number of medical and urological conditions associated with nocturia in a cohort of older men who were primary-care enrolees, and to assess the feasibility and efficacy of using a multicomponent intervention to reduce nocturia and its bother. SUBJECTS AND METHODS Men aged > or =50 years and with two or more episodes of nocturia were recruited from the primary-care clinics at one Veterans Affairs Medical Center to participate in a 4-week, open-label, prospective pilot study. A multicomponent intervention composed of behavioural therapy and targeted drug therapy was administered according to a specified protocol based upon identified risk factors for nocturia.

Sleep-disordered breathing and 24-hour blood pressure pattern among older adults.

Background: To examine the association between sleep-disordered breathing (SDB) and 24-hour blood pressure (BP) pattern among community-dwelling older adults.

Methods: A convenience sample of 70 community-dwelling older adults, recruited from senior housing, community centers, and learning centers, were admitted to General Clinical Research Center, Emory University Hospital, Atlanta, Ga. Information regarding demographic and clinical history was obtained using questionnaires.

Correlates of self-reported nocturia among community-dwelling older adults.

Background: Nocturia is a common and bothersome problem with multifactorial etiology. This study examines clinical factors that are associated with nocturia among community-dwelling older adults.

Methods: A questionnaire-based survey was conducted among a convenience sample of community-dwelling older adults.

Effects of hypertension and hypercholesterolemia on cognitive functioning in patients with alzheimer disease.

This study investigated the relationship between the vascular comorbidities (VCs) of hypertension and hypercholesterolemia and the cognitive phenotype of Alzheimer disease (AD). Seventy-four AD patients underwent objective measurement of blood pressure and serum cholesterol levels, and they received a detailed neuropsychologic evaluation examining attention, memory, language, visuomotor/visuospatial skills, and executive functioning. Multiple regression analyses controlling for demographic variables, overall cognitive status, and the presence of diabetes/cardiac disease indicated that an increase in the number of VCs, but not their severity, was associated with poorer verbal and visual recall, visuoconstructive and spatial analysis, verbal reasoning, and set shifting.

Sleep-disordered breathing and cardiovascular disease in the Bay Area Sleep Cohort.

Study Objectives: To examine the relationship between sleep-disordered breathing (SDB) and cardiovascular disease among community-dwelling older adults. Previous studies have suggested relatively stronger associations between SDB and such morbidity in middle-aged, relative to elderly, populations.

Design: Cross-sectional analysis of an elderly ambulatory, non-clinic-based cohort (Bay Area Sleep Cohort, BASC) SETTING: Community population studied in a sleep laboratory

Participants: One hundred twenty-nine older adults (mean [+/- SD] age = 72.

Polysomnographic and clinical correlates of behaviorally observed daytime sleep in nursing home residents.

Background: The causes of daytime sleepiness among nursing home residents have not been well recognized. This study examines clinical and polysomnographic factors that are associated with daytime sleepiness among nursing home residents.

Methods: One hundred seventy-four nursing home residents from eight nursing homes in Atlanta, Georgia, participated in the study.

Clinical characteristics of obstructive sleep apnea in community-dwelling older adults.

Objectives: To examine whether traditional risk factors are common in older adults with obstructive sleep apnea (OSA).

Design: Cross-sectional study.

Setting: Atlanta, Georgia.