Early impact of hormone replacement therapy on vascular hemodynamics detected via ocular colour Doppler analysis.

Objective: To determine the effects of hormone replacement therapy (HRT) on ocular blood flow.

Study Design: In a prospective controlled study, 40 healthy women who presented to the menopause clinic between December 2000 and December 2001 were randomly assigned into the study. The HRT-receiving group was administered estradiol 17-valerate 2 mg the first 11 days, and estradiol 17-valerate 2 mg plus ciproterone acetate 1 mg the next 10 days of the monthly cycle for 6 months.