Efficiency of antibiotic-loaded polymethylmethacrylate rods for treatment of the implant-related infections in rat spine.

Study Design: A study of local treatment of the implant-related infections in animal spine.

Objective: : This study aims to investigate the efficiency of antibiotic-loaded polymethylmethacrylate rods for treatment of the implant-related infections.

Summary Of Background Data: Today's implant-related vertebral infections are challenging in spinal surgery.

Implant-related infection model in rat spine.

Objective: The rate of postoperative infections is approximately 1% in spine surgery. However, when metal implants are used, postoperative infection rates significantly increase and were reported between 2.1 and 8.