Publications by authors named "Endalamaw Tesfa"

Article Synopsis
  • Three common variants of the eNOS gene (G-894T, T-786C, and VNTR intron-4) have been studied for their potential link to preeclampsia (PE), although results vary.
  • A meta-analysis reviewing 47 studies involving nearly 14,000 pregnant women was conducted using various databases and statistical methods to evaluate this association.
  • The findings indicated that women with TT and CC genotypes at the 894 and 786 positions of the eNOS gene have a higher risk of developing PE, while no significant association was found for the VNTR intron-4 variant.
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Background And Aims: Pre-eclampsia (PE) is a pregnancy-related syndrome that occurs after 20 weeks of pregnancy. The current study was designed to evaluate the determinants of PE in pregnant women following antenatal and delivery services.

Methods: An institution-based case-control study was performed in governmental hospitals of Bahir Dar city.

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Background And Aims: Burdens of occupational exposure like insoluble dust particles and chemicals in the respiratory tract leads to impaired clearance. This study aims to assess the prevalence of obstructive lung patterns and actual spirometric result in Ethiopia at different workplaces.

Methods: Five electronic databases such as: PubMed, HINARI, Science Direct, Google Scholar, and African Journals Online were searched in studies conducted from 2010 to 2021.

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Background: The serum lipid and immunohematological values of tuberculosis lymphadenitis (TBLN) patients is poorly documented relative to pulmonary tuberculosis (PTB) cases. Therefore, the aim of this study was to investigate the serum lipid and immunohematological values of patients with TBLN in comparison with PTB (PTB) patients.

Methods: An institution-based comparative cross-sectional study was conducted in Northwest Ethiopia from March to December 2021.

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Pre-eclampsia (PE) is a pregnancy-related disorder characterized by hypertension and proteinuria occurring after 20 weeks of gestation. Several studies have been performed to determine the serum magnesium (Mg) level in PE, but most report inconclusive results. Consequently, this study was designed to resolve this controversy among African women.

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Article Synopsis
  • - Pre-eclampsia (PE) negatively impacts pregnant women and their babies, and despite extensive research, effective diagnostic tools are still lacking; this study aimed to assess serum uric acid, blood urea, and creatinine levels to predict PE.
  • - A case-control study involving pregnant women was conducted, measuring serum levels using an automated analyzer, and the statistical analysis revealed significantly higher uric acid and blood urea levels in women with PE compared to those without.
  • - Findings indicated that serum uric acid and blood urea levels could potentially serve as indicators for pre-eclampsia, with specific cutoff points determined for effective screening, while creatinine levels showed no significant differences.
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Diabetes mellitus (DM) is a public health problem in developing as well as developed nations. DM leads to many complications that are associated with higher morbidity and mortality worldwide. Therefore, the current study was planned to assess the prevalence and risk factors of type-2 DM in Ethiopian population.

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Background: A number of epidemiological studies were performed to know the prevalence of and the risk factors for hypertension. However, these studies reported inconsistent results. As a result, this systematic review and meta-analysis were planned to generate representative data on the prevalence of and risk factors for hypertension among the Ethiopian adult population.

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Some studies have reported the association between maternal serum zinc (Zn) levels and pre-eclampsia. However, many studies have reported controversial results. Hence, this systematic review and meta-analysis was planned to generate summarized evidence on the association between maternal serum Zn levels and pre-eclampsia in African women.

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Introduction: Some studies have reported the association between maternal serum lipid profile abnormalities and pre-eclampsia. However, many studies have reported controversial results. Hence, this systematic review and meta-analysis was planned to generate summarized evidence on the association between maternal serum lipid profiles and pre-eclampsia in African women.

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Introduction: Hypertensive disorder of pregnancy is the second commonest causes of maternal death globally. Different public health studies were conducted on hypertensive disorder of pregnancy which presented inconsistent result. Therefore, this systematic review and meta-analysis was commenced to summarize the findings conducted in several parts of the country and to generate the nationwide representative data on the prevalence and risk factors of hypertensive disorder of pregnancy in Ethiopia.

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Objective: HAART had significantly improved the quality of life of HIV patients. However, it results different adverse effects such as: hepatotoxicity, nephrotoxicity, lipodystrophy, anemia, diarrhea, psychiatric disorder and others. Therefore, this comparative cross sectional study was designed to investigate liver enzyme elevation in patients taking HAART compared with treatment naïve controls at Debre Berhan Referral Hospital.

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Objective: This health institution based cross section study was designed to determine factors associated with utilization of long term family planning methods among women reproductive age attending Bahir Dar health facilities.

Result: A total of 406 women were interviewed in this study. The mean age (standard deviation) of the study participants was 26.

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In Ethiopia, neonatal mortality has been declined since the declaration of Millennium Developmental Goals, but the rate was slower since 2006. Thus, this study was designed to assess the determinants of neonatal mortality (NM) in North Shoa Zone. A community based case-control study was conducted on 84 cases and 252 controls.

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