Publications by authors named "Enass Bassiouny"
Background: Hypercalcemia has been associated with hypergastrinemia in humans. Hypergastrinemia could be responsible for gastrointestinal (GI) signs in dogs with primary hyperparathyroidism (PHPT).
Hypothesis/objectives: (a) Determine whether hypergastrinemia occurs in dogs with PHPT, (b) assess for potential correlations among ionized calcium (iCa), parathyroid hormone (PTH), and serum gastrin concentrations, and (c) determine whether gastrin concentrations decrease after management of PHPT.
Article Synopsis
- The study aimed to establish a reference interval (RI) for serum gastrin levels in dogs after a 12-hour fasting period, addressing challenges with the traditional 24-hour fasting approach.
- Using data from 55 healthy adult dogs, the RI was determined to be 15.1-78.9 ng/L, with confidence intervals for the lower and upper limits being 14.0-22.9 and 68.3-83.0 ng/L, respectively.
- The research found no significant correlations between serum gastrin levels and factors like age, weight, sex, or total calcium concentration, highlighting a need for further studies on how hypercalcemia might impact gastrin levels in dogs.