Publications by authors named "Enas Ismail"

This work presents a review of the therapeutic modalities and approaches for cancer treatment. A brief overview of the traditional treatment routes is presented in the introduction together with their reported side effects. A combination of the traditional approaches was reported to demonstrate an effective therapy until a few decades ago.

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Temporomandibular disorders (TMD) affect a significant portion of the population, with profound psychological, behavioral, and social repercussions. Recent investigations have explored the genetic basis underlying pain perception in individuals with TMD, aiming to elucidate the role of specific genetic factors in modulating the condition. Notably, genetic variations have been implicated in the pathogenesis of TMD, particularly genes involved in pain perception pathways.

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Article Synopsis
  • Root canal failure is a common issue in dentistry, often caused by bacteria like Enterococcus faecalis, Candida albicans, and Staphylococcus aureus; researchers are exploring alternative antimicrobial root canal sealers using nanomaterials for better effectiveness.
  • The systematic review aims to compare the antimicrobial properties of traditional root canal sealers and newer ones that incorporate green synthesized nanoparticles, focusing on studies published from 2010 to 2024.
  • A comprehensive protocol for the review has been registered, with ethical approval obtained, and the methodology follows strict guidelines to ensure valid and reliable results, including using several scientific databases for data collection.
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A comparative study was applied to investigate the potential of (bottlebrush) flower extract (BBE) and (pomegranate) peel extracts (PPE) for the sustainable synthesis of the silver nanoparticles, Ag-BBE and Ag-PPE, respectively. The synthesis process of Ag NPs using the selected extracts was applied under optimized conditions. Hence, the effect of the selected plant's type on the different characteristics of the synthesized green Ag NPs was investigated.

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In this study, we report the successful synthesis of a phenol-formaldehyde-pyrazole (PF-PYZ) compound through the surface functionalization of phenol-formaldehyde (PF) with pyrazole (PYZ). The resulting mixture was subjected to comprehensive characterization using a range of analytical techniques, including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and thermogravimetric analysis (TGA). The newly synthesized PF-PYZ material effectively removes Cr(VI) ions.

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Fungal infections caused by () are one of the most prevalent types of oral disorders in the elderly. It has been reported that drug resistance to fungal pathogens poses a severe risk to global healthcare systems and public health. Therefore, the goal of this work is to investigate the cytotoxic and antifungal properties of silver nanoparticles (AgNPs) produced using three different natural extracts: , , and .

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Three-dimensional (3D) scaffolds are attracting great concern for bone tissue engineering applications. However, selecting an appropriate material with optimal physical, chemical, and mechanical properties is considered a great challenge. The green synthesis approach is essential to avoid the production of harmful by-products through textured construction, sustainable, and eco-friendly procedures.

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Fabrication of scaffolds for nerve regeneration is one of the most challenging topics in regenerative medicine at the moment, which is also interlinked with the development of biocompatible substrates for cells growth. This work is targeted towards the development of green biomaterial composite scaffolds for nerve cell culture applications. Hybrid scaffolds of hydroxyethyl cellulose/glycine (HEC/Gly) composite doped with different concentrations of green ruthenium oxide (RuO) were synthesized and characterized via a combination of different techniques.

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Article Synopsis
  • Plant extracts, especially one containing a compound called hypoxoside, were used to create silver nanoparticles (AgNPs) through a green synthesis method.
  • The resulting AgNPs were characterized in size, showing HE-AgNPs at about 24.3 nm and HP-AgNPs at roughly 3.9 nm, and tested for their antimicrobial and anticancer activities.
  • HE-AgNPs exhibited strong antibacterial effects and varying cytotoxicity against cancer cells, while HP-AgNPs showed even better selectivity across both tested glioblastoma cell lines, highlighting hypoxoside's role as a significant reducing and capping agent in nanoparticle synthesis.
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In this study, procyanidin dimers and total extract (LSTE) were employed in the synthesis of silver nanoparticles (AgNPs) and characterized by ultraviolet-visible (UV-Visible) spectroscopy, high-resolution transmission electron microscopy (HRTEM), selected area electron diffraction (SAED), X-ray diffraction (XRD), and dynamic light scattering (DLS) techniques. AgNPs of about 2-7 nm were obtained. DLS and stability evaluations confirmed that the AgNPs/procyanidins conjugates were stable.

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In this study, procyanidins fractions of dimers and trimers (F1-F2) from the total extract (LSTE) were investigated for their chemical constituents. The total extract and the procyanidins were employed in the synthesis of gold nanoparticles (Au NPs) and fully characterized. Au NPs of 6, 24 and 21 nm were obtained using LSTE, F1 and F2 respectively.

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Unlabelled: Background Venous thromboembolism is the most common preventable cause of hospital death. Despite that, there is still a large gap between what we know about venous thromboembolism prophylaxis and what is happening in current practice. Objective To evaluate VTE prophylaxis in Al-Basheer hospital and assess the extent of agreement of physicians' practice with the guidelines.

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Introduction: Psoriasis arthritis (PsA) is a chronic inflammatory arthritis of joints of uncertain pathogenesis. PsA may lead to severe disabilities even in the absence of any clinical symptom. Therefore, PsA diagnosis in its early stages is critical.

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Varicocele is a common male disease defined as the pathological dilatation of the pampiniform plexus and scrotal veins with venous blood reflux. Varicocele usually impairs the scrotal thermoregulation via a hemodynamic alteration, thus inducing an increase in cutaneous temperature. The investigation of altered scrotal thermoregulation by means of thermal infrared imaging has been proved to be useful in the study of the functional thermal impairment.

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Synopsis of recent research by authors named "Enas Ismail"

  • - Enas Ismail's recent research primarily focuses on the synthesis and characterization of nanoparticles, particularly using green and sustainable methods involving natural extracts, with applications in biomedical fields, such as dentistry and tissue engineering.
  • - A significant finding in Ismail's work includes the exploration of genetic factors influencing pain perception in temporomandibular disorders, highlighting the role of catechol-O-methyltransferase gene activity in South African patients.
  • - Ismail has also investigated the antimicrobial properties of innovative root canal sealers and green-synthesized silver nanoparticles, emphasizing their potential effectiveness against common oral pathogens and their biocompatibility for various medical applications.