Colchicine: A Dual Therapeutic Target for Trichinellosis.

Purpose: Trichinellosis affects around 11 million people globally. Treatments for this medical condition are limited by adverse effects and resistance, emphasising the importance of effective and safe therapies. Consequentially, we sought to study colchicine's synergistic effects with atorvastatin or acetazolamide in the treatment of Trichinella spiralis (T.

Toxoplasma gondii Suppresses Th2-Induced by Infection and Downregulates Serine Protease Genes Expression: A Critical Role in Vaccine Development.

Background: coinfection can modify host immune responses and the severity and spread of other parasites. We investigated how and infections counter-regulate each other's immune responses.

Methods: The parasite burden, the expression of rhoptry kinase ROP18 and putative serine protease (TsSP), the IgG1 and IgG2a responses, besides histopathological and immunohistochemical staining with iNOS and arginase were used to evaluate the dynamics of coinfection.

Role of interferon gamma in SARS-CoV-2-positive patients with parasitic infections.

Background: By 27 June 2020, almost half a million people had died due to COVID-19 infections. The susceptibility and severity of infection vary significantly across nations. The contribution of chronic viral and parasitic infections to immune homeostasis remains a concern.

The relationship between toxoplasmosis and different types of human tumors.

Introduction: Toxoplasma gondii is an intracellular protozoan that may disrupt the traditional cell barriers against cancer, allowing the accumulation of oncogenic mutations over time. Our research aimed to explore the relationship between T. gondii infection and tumor development.