Diabetes mellitus (DM) is a metabolic disorder of the proteins, lipids, and carbohydrates, results in hyperglycemia. Abnormalities in the function of insulin on target cells, its release from beta cells, or both may contribute to DM. The purpose of this research was to assess the progression of diabetic retinopathy (DR) to the levels of serum brain-derived neurotrophic factor (BDNF), glycated hemoglobin (HbA1c), and biochemical parameters.
View Article and Find Full Text PDFPurpose: To investigate the relationship between serum brain-derived neurotrophic factor (BDNF) and changes in macular perfusion in different stages of diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA).
Materials And Methods: The study was conducted on 72 eyes of people with type 2 diabetes mellitus (DM). They were divided into five groups based on their DR stage: no DR (nDR), mild and moderate nonproliferative DR, severe nonproliferative DR, active proliferative DR (aPDR), and stable PDR.