Publications by authors named "Enamul Kabir Talukder"
Article Synopsis
- SARS-CoV-2, the virus that causes COVID-19, has led to nearly 4.9 million deaths globally, yet no specific treatment exists to fight it; the virus infects host cells by attaching to the ACE2 receptor using its Spike protein.* -
- This study investigates natural compounds from the perennial rue herb (Ruta graveolens) as possible inhibitors of the Spike protein, with 53 compounds initially screened and 12 identified as potential candidates.* -
- Four compounds—Amentoflavone, Agathisflavone, Vitamin P, and Daphnoretin—showed promise in blocking the Spike protein and have favorable safety profiles; in vitro tests revealed these extracts can effectively inhibit the
(L.) Roxb. is an ethno-medicinal herb used by rural and tribal people of the Satpura region of Madhya Pradesh in India and the Phatthalung Province of Thailand for treating rheumatism, bronchitis, ringworm, itches, leprosy, dyspepsia, liver disorders and heart disorders.
View Article and Find Full Text PDFMinichromosome maintenance complex component 7 (MCM7) belongs to the minichromosome maintenance family that is important for the initiation of eukaryotic DNA replication. Overexpression of the MCM7 protein is relative to cellular proliferation and responsible for aggressive malignancy in various cancers. Mechanistically, inhibition of MCM7 significantly reduces the cellular proliferation associated with cancer.
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