Botanical Origin Influence on Some Honey Physicochemical Characteristics and Antioxidant Properties.

Five types of honey (multifloral, sunflower, linden, rapeseed, and acacia), from Southern Romania, were classified using chemometrics methods coupled with IR spectroscopy. The botanical origin's effect on the physicochemical characteristics of honey was studied to highlight the most valuable plant source of honey. Except for antioxidant activity, the moisture, ash, electrical conductivity (EC), pH, free acidity (FA), total sugar content (TSC), hydroxymethylfurfural (HMF), total phenolic (TPC), tannin (TTC), and flavonoid content (TFC) were significantly influenced by the botanical origin of the honey.

Modelers of students' entrepreneurial intention during the COVID-19 pandemic and post-pandemic times: The role of entrepreneurial university environment.

This paper examines the shaping factors, drivers, and impact credentials of students' entrepreneurial intention during the COVID-19 pandemic. The proposed framework addresses the antecedents of entrepreneurial intention among students in Romania, focusing on three focal constructs, namely, risk-taking, proactiveness, and innovativeness, with a keen focus on the mediation effect of the entrepreneurial university environment. The study used self-reported data collected through an online questionnaire during November 2020-February 2021 from a sample of 1,411 students in western Romania.

Effect of Pd/ZnO Morphology on Surface Acoustic Wave Sensor Response.

Laser deposition was used to obtain Pd/ZnO bilayers, which were used as sensing layers in surface acoustic wave (SAW) sensors. The effect of laser deposition parameters such as deposition pressure, laser energy per pulse, laser wavelength or pulse duration on the porosity of the Pd and ZnO films used in the sensors was studied. The effect of the morphology of the Pd and ZnO components on the sensor response to hydrogen was assessed.

Delineation of Molecular Lesions in Acute Myeloid Leukemia Patients at Diagnosis: Integrated Next Generation Sequencing and Cytogenomic Studies.

Acute myeloid leukemia (AML) is a heterogeneous disorder characterized by a wide range of genetic defects. Cytogenetics, molecular and genomic technologies have proved to be helpful for deciphering the mutational landscape of AML and impacted clinical practice. Forty-eight new AML patients were investigated with an integrated approach, including classical and molecular cytogenetics, array-based comparative genomic hybridization and targeted next generation sequencing (NGS).

Children's Preferences for Oral Dosage Forms and Their Involvement in Formulation Research via EPTRI (European Paediatric Translational Research Infrastructure).

The paucity of evidence-based data on formulation characteristics preferred by the children is known to limit the design of tailored paediatric dosage forms. The European Paediatric Translational Research Infrastructure (EPTRI) commissioned a study to evaluate children's dosage forms perceived preferences in some European countries and explore the feasibility of using the young persons advisory groups (YPAGs) to involve children in formulation research. An online, age-adapted survey was developed and translated into six languages.

New carbocyclic N(6)-substituted adenine and pyrimidine nucleoside analogues with a bicyclo[2.2.1]heptane fragment as sugar moiety; synthesis, antiviral, anticancer activity and X-ray crystallography.

New nucleoside analogues with an optically active bicyclo[2.2.1]heptane skeleton as sugar moiety and 6-substituted adenine were synthesized by alkylation of 6-chloropurine intermediate.

The evaluation of the outcome in myelodysplastic patients by using non-cytogenetic prognostic scores.

Unlabelled: Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic stem cell disorders; they are characterized by ineffective hematopoiesis and a predilection to the development of acute myeloid leukemia (AML). For a rapid evaluation of the outcome in myelodysplastic patients non-cytogenetic prognostic scores can be used.

Aim: This study proposed to demonstrate that age and gender are important factors in the outcome of the patients diagnosed with myelodysplastic syndrome.

Clinical impact of contrast-enhanced computed tomography combined with low-dose (18)F-fluorodeoxyglucose positron emission tomography/computed tomography on routine lymphoma patient management.

This study evaluated the clinical impact of contrast-enhanced computed tomography (CECT) on routine management of patients with lymphoma. Over a 1-year period, 237 CECT scans were performed prospectively in 163 patients after low-dose (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT). Scans were performed at staging (n = 41), interim (n = 73), post-therapy (n = 115) and follow-up (n = 8).

New carbocyclic nucleoside analogues with a bicyclo[2.2.1]heptane fragment as sugar moiety; synthesis, X-ray crystallography and anticancer activity.

An amine group was synthesized starting from an optically active bicyclo[2.2.1]heptane compound, which was then used to build the 5 atoms ring of a key 6-chloropurine intermediate.

Chronic lymphocytic leukemia followed by myelodysplastic syndrome and erythroleukemia.

CLL patients are more exposed to develop a second neoplasm, but the association. CLL-MDS is an unusual one. We present the case of a 61-year-old male patient, diagnosed with chronic lymphocytic leukemia in 2007, who developed myelodysplastic features three years later and then acute myeloid leukemia.

Conformational transitions in polyelectrolyte adsorption.

The mole fraction X of nucleic acid chromophores, adsorbed on cationic and anionic exchange chromatography paper disks, was calculated [O.L. Hörer and A.

The distribution of nucleic acid chromophores at cellulose-water interfaces. 2. Thermodynamic parameters.

A Previous theoretical' model (O. L. Hörer, Adriana Grigorescu Rev.

Menu software for the processing of spectrofluorometry analysis.

Menu software is presented for the computer-assisted spectrofluorometric analysis of the 3,4-benzopyrene contents of different samples, determined by a method implying the addition of fluorescent substances in the presence of other fluorochromes. A system consisting of an SPF-500 spectrofluorometer interfaced to a Felix-M18 microcomputer was used for this purpose. The advantages of the computer-assisted processing of spectrofluorometric analyses are discussed.

Automation of laboratory instrumentation--recent achievements in the Stefan S. Nicolau Institute of Virology.

An automated system consisting of an SPF-500 spectrofluorometer interfaced to a Felix-M18 microcomputer was provided with a series of additional accessories benefitting from the inputs and outputs through the interface. An adequate set of programs for computer-controlled operations was developed. The system has allowed the performance of more than 15,000 absorption, emission and light scattering determinations.

RNA absorbances in modified cellulose disks.

Bichromatic spectrophotometry determinations were performed on Whatman chromatographic paper disks impregnated with rRNA solutions of different concentrations, at ionic strengths ranging from nearly 0 to 1.4 M. The disks consisted of cellulose, either native or modified (by grafting of carboxymethyl, phosphate, Ecteola or DEAE groups, or by loading with silica gel).

2-propanol dependent RNA absorbance.

RNA absorbances Ad were determined by bichromatic spectrophotometry at 240, 260 and 280 nm, versus 350 nm values, on paper disks containing different 2-propanol concentrations and NaCl amounts. No significant differences in terms of the NaCl content could be observed at alcohol concentrations higher than 70%; the maximum Ad value was found to correspond to about 50% 2-propanol. The possible phenomena implied in the absorbance changes are discussed taking into account the peculiar action of 2-propanol on the water structure and content in the bulk phase within the paper capillaries and inside the macromolecular and aggregation structures of RNA and cellulose.

Nucleic acid spectrophotometry on paper disks.

A bichromatic spectrophotometry study in the near UV spectral range was performed on paper disks impregnated with DNA and RNA in NaCl solutions of different concentrations. Absorbance curves plotted versus a NaCl molarity log-scale degree of polymerization and the solubility of the polynucleotide. The -a/b value, determined by a previously reported equation, appeared to be constant for a given nucleic acid, irrespective of the wavelength in the spectral range 205-280 nm.

RNA--streptomycin interaction on cellulose.

Bichromatic paper disk spectrophotometry allowed the demonstration of an analogy between the increase in the solubility of highly polymerized RNA complexed with streptomycin cations (which accounts for the preservation in vivo of the infectivity of a viral RNA--streptomycin complex) and the effect of a cellulose/solution interface on the distribution of the highly polymerized RNA.

Felix-M18 microcomputer-controlled automation of spectrofluorometric measurements with applications in virology.

A system consisting of an Aminco SPF-500 spectrofluorometer interfaced to the Felix-M18 microcomputer was used in the automation of spectrofluorometric measurements with applications in virology. Programs, routines and subroutines in BASIC and in assembly language allow the operation of the spectrofluorometer and the processing of photometric data. The high efficiency of the system is illustrated by an application: the characterization of the fluorescence anisotropy value in polarized light of an influenza virus suspension preincubated with a fluorescent probe.