Reference ranges of peripheral-muscle oxygenation in term neonates delivered by Caesarean section during immediate transition after birth.

Aim: To establish reference ranges of peripheral-muscle regional oxygen saturation (prSO) and peripheral fractional tissue oxygen extraction (pFTOE) during the first 15 min after birth in stable term neonates.

Methods: Secondary outcome parameters of prospective observational studies in healthy term neonates delivered by Caesarean section were analysed. prSO was measured on the right forearm using the INVOS 5100C monitor.

Peripheral muscle fractional tissue oxygen extraction in stable term and preterm neonates during the first 24 h after birth.

Background: Peripheral muscle fractional tissue oxygen extraction (pFTOE) represents the relative extraction of oxygen from the arterial to venous compartment, providing information about dynamic changes of oxygen delivery and oxygen consumption. The aim of the present study was to establish reference values of pFTOE during the first 24 h after birth in stable term and late preterm neonates.

Methods: The present study is a analysis of secondary outcome parameters of prospective observational studies.

Peripheral fractional oxygen extraction measured with near-infrared spectroscopy in neonates-A systematic qualitative review.

Background: Peripheral fractional oxygen extraction (pFOE) measured with near-infrared spectroscopy (NIRS) in combination with venous occlusion is of increasing interest in term and preterm neonates.

Objective: The aim was to perform a systematic qualitative review of literature on the clinical use of pFOE in term and preterm neonates and on the changes in pFOE values over time.

Methods: A systematic search of PubMed, Embase and Medline was performed using following terms: newborn, infant, neonate, preterm, term, near-infrared spectroscopy, NIRS, oximetry, spectroscopy, tissue, muscle, peripheral, arm, calf, pFOE, OE, oxygen extraction, fractional oxygen extraction, peripheral perfusion and peripheral oxygenation.

Fetal Hemoglobin and Cerebral Tissue Oxygenation during Immediate Postnatal Transition.

Introduction: Concentration of fetal hemoglobin (HbFc) in human neonates determines oxygen-carrying capacity of blood and the position of oxyhemoglobin dissociation curve. Near-infrared spectroscopy enables the measurement of regional cerebral tissue oxygen saturation (rScO2) and in combination with measurements of pulsatile arterial oxygen saturation (SpO2), the calculation of cerebral fractional tissue oxygen extraction (cFTOE).

Methods: We aimed to investigate the impact of HbFc on rScO2, cFTOE, and SpO2 in preterm and term neonates during the first 15 min after birth.

Three Physiological Components That Influence Regional Cerebral Tissue Oxygen Saturation.

Near-infrared spectroscopy (NIRS) measurement of regional cerebral tissue oxygen saturation (rcStO2) has become a topic of high interest in neonatology. Multiple studies have demonstrated that rcStO2 measurements are feasible in the delivery room during immediate transition and resuscitation as well as after admission to the neonatal intensive care unit. Reference ranges for different gestational ages, modes of delivery, and devices have already been published.