Publications by authors named "En-bin Liu"

Objective: To study the clinicopathologic features and differential diagnosis of splenic B-cell marginal zone lymphoma (SMZL) involving bone marrow.

Methods: The clinical and pathologic features of 22 patients with SMZL were retrospectively studied. Immunophenotypic analysis was carried out by flow cytometry and immunohistochemistry.

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Objective: To explore the diagnosis and differential diagnosis of refractory cytopenia of children (RCC) according to WHO classification, and discuss the relationship between the cytology reviewed by hematologists and histology reviewed by pathologists.

Methods: We selected 50 non-severe aplastic anemia cases from 2007 - 2010 in our hospital and collected clinical data. Experienced hematologists and pathologists evaluated bone marrow biopsy and smear respectively.

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Objective: To explore the hematopathologic features of T-cell large granular lymphocytic leukemia (T-LGLL).

Methods: A retrospective analysis of the clinical presentation, bone marrow morphology, immunophenotyping and T-cell receptor gene rearrangement status were performed in 19 patients with T-LGLL.

Results: Of 19 patients, the most frequent hematological abnormalities were anemia and neutropenia (16/19 and 17/19 patients, respectively).

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Objective: To study the clinicopathologic features of aggressive natural killer cell leukemia (ANKL).

Methods: The clinical and pathologic features were analyzed in 10 patients with ANKL. The complete blood count, peripheral blood smears, bone marrow aspirates and bone marrow biopsies were studied.

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Objective: To explore the clinicopathologic features of lymphoplasmacytic lymphomas (LPL).

Methods: Routine histological examination was performed on hematoxylin-eosin stained sections of 24 bone marrow biopsies and available 6 concurrent lymph node specimens. Immunohistochemistry study was performed using EliVision methods.

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Aiming at the deficiencies in the researches about the probability distribution model for mixed forests tree measurement factors, a joint maximum entropy probability density function was put forward, based on the maximum entropy principle. This function had the characteristics of 1) each element of the function was linked to the maximum entropy function, and hence, could integrate the information about the probability distribution of measurement factors of main tree species in mixed forests, 2) the function had a probability expression of double-weight, being possible to reflect the characteristics of the complex structure of mixed forests, and accurately and completely reflect the probability distribution of tree measurement factors of mixed forests based on the fully use of the information about the probability distribution of measurement factors of main tree species in mixed forests, and 3) the joint maximum entropy probability density function was succinct in structure and excellent in performance. The model was applied and tested in two sampling plots in Tianmu Mountain Nature Reserve.

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Objective: To investigate the clinicopathologic features, diagnosis, differential diagnosis and the prognosis of hairy cell leukemia (HCL).

Methods: Fifteen splenectomy specimens of HCL patients were investigated retrospectively using HE and immunohistochemistry in correlation with the follow-up information.

Results: (1) The male to female ratio was 2.

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Objective: To study the clinicopathologic features of peripheral T-cell lymphoma, unspecified (PTL-U) with follicular pattern.

Methods: The clinical data, hematoxylin and eosin-stained sections of lymph node biopsies and follow-up data of 18 cases of PTL-U associated with follicular growth pattern were reviewed and studied. Eight cases of reactive lymphoid hyperplasia were used as controls.

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Primary and metastatic carcinomas have a reactive stroma characterized by many myofibroblasts. These cells have also been documented in nonepithelial malignancies, such as sarcomas, malignant melanoma, and lymphoid tumors but in generally far fewer numbers. In non-Hodgkin's lymphoma, Hodgkin's disease, and leukemia, myofibroblasts are rather rarely documented.

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Objective: To investigate the role of bone marrow biopsy (BMB) in diagnosis and differential diagnosis for chronic eosinophilic leukemia (CEL).

Methods: Clinical and pathological features of thirteen CEL patients were analyzed retrospective. Routine histologic examination was performed on H-G-E, reticulin fiber and toluidine blue stained sections of plastic material emdedded samples of bone marrow biopsies.

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Objective: To identify the side effect of all-trans retinoic acid (ATRA), and improve early therapeutic response in patients with acute promyelocytic leukemia (APL).

Method: The first case of Sweet's syndrome (SS) developed in a APL patient treated with ATRA was reported in mainland of China, and reviewed correlative literature.

Results: Only 14 cases of SS associated with ATRA therapy in APL have been reported in the literature, including the present case.

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Objective: To investigate the significance of clinicopathological stage of chronic idiopathic myelofibrosis (CIMF) in WHO classification of 2001.

Methods: Histopathological analysis of bone marrow biopsy plastic-embedded sections stained with H-G-E and Gomori's stains and clinical features of 113 cases previously diagnosed as primary myelofibrosis (PMF) and 48 cases MPD-U (total of 161 cases which including male 79 and female 82) were studied retrospectively.

Results: There was no significant differences on the clinical features among the cellular phase, collagen fiber phase, sclerotic phase and osteomyelosclerosis of 113 previously diagnosed patients.

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The diagnosis of lymphoma bone marrow involvement (LBMI) is mainly based on bone marrow biopsy. Pathology of LBMI in Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL) are different. The morphology, distribution patterns and immunophenotype of most tumor cells in bone marrow are consistent with those in extramedullary sites, but few may show some discrepancy.

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Objective: To study the characteristics histologic and cytologic features and clinical usefulness of plasma cell myeloma (PCM) subtyping according to WHO PCM classification.

Methods: Bone marrow biopsy plastic-embedded sections were stained with H-G-E and Gomori's stains, and bone marrow aspirate smears were stained with Wright's stain. The clinicopathologic findings were then analyzed.

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