Publications by authors named "En-Zhong Jin"
Article Synopsis
- The study aimed to compare ultra-widefield swept-source optical coherence tomography angiography (SS-OCTA) and fluorescein angiography (FA) for detecting diabetic retinopathy (DR) lesions in patients.
- It involved 23 patients with DR and 23 healthy controls, analyzing parameters like fovea avascular zone (FAZ) size and microaneurysm count using both imaging techniques.
- The results showed that while SS-OCTA and FA provided similar measurements for some parameters, SS-OCTA showed fewer microaneurysms than FA, suggesting it is a reliable and noninvasive alternative for assessing DR microvasculature.
Aim: To report an atypical Adams-Oliver syndrome (AOS) family with typical ocular signs of familial exudative vitreoretinopathy (FEVR).
Methods: A patient with visible avascular area and obvious non-perfusion zone in the peripheral retina with systemic signs of AOS was reported. Familial and personal characteristics were collected for the patient and his sister.
An Insertion Variant in CRH Confers an Increased Risk of Central Serous Chorioretinopathy.
Invest Ophthalmol Vis Sci
August 2022
Article Synopsis
- A study aimed to identify a new variant of the corticotropin-releasing hormone (CRH) gene that is significant for patients with central serous chorioretinopathy (CSC).
- Using genetic analysis in families and individual cases, researchers discovered a specific variant (Gln52insPro) in the CRH gene that was linked to CSC in two Chinese families.
- The variant was found to be strongly associated with CSC in a larger group of Chinese patients, suggesting an important role of the stress response system in the development of CSC and highlighting potential new treatment approaches.
Aim: To evaluate the efficacy and safety of ruthenium-106 (Ru) plaque radiotherapy at a dose (>50 Gy) higher than recommended (29-50 Gy) for treatment of circumscribed choroidal hemangioma (CCH) in Chinese patients.
Methods: This retrospective study included 25 symptomatic CCH patients undergoing Ru plaque brachytherapy involving 25 eyes between January 2005 and August 2016. Ophthalmic examination was performed at the baseline and at each post-treatment follow-up visit, using best-corrected visual acuity (BCVA), dilated fundus examination, and B-scan ultrasonography.
Aim: To evaluate the real-life clinical outcomes of intravitreal injection of conbercept combined rescue therapy for polypoidal choroidal vasculopathy (PCV).
Methods: This was an open label, single center, and interventional study. All enrolled patients were treated initially with three consecutive monthly intravitreal conbercept injections (0.