Publications by authors named "En Ling Zhan"
In insect ionotropic γ-aminobutyric acid receptor (iGABAR) subunits, only resistance to dieldrin (RDL) can be individually and functionally expressed . In lepidopteran, two to three RDL subtypes are identified; however, their physiological roles have not been distinguished . In this study, Rdl1 and Rdl2 of were individually knocked out using CRISPR/Cas9, respectively.
View Article and Find Full Text PDFBroflanilide is a novel insecticide with a unique mode of action on the insect GABA receptor and is registered worldwide for the control of agricultural pests. It shows high efficacy in controlling the fall armyworm (FAW) Spodoptera frugiperda, which is a destructive pest to various crops. FAW was exposed to sublethal concentrations of broflanilide to determine its impact on insect development.
View Article and Find Full Text PDFArticle Synopsis
- The fall armyworm (FAW) is a major pest that invaded China in 2019 and severely damages maize crops.
- Recent research shows that three GABAR-targeted insecticides—broflanilide, fluralaner, and fipronil—are effective in controlling FAW larvae, with varying levels of oral toxicity.
- The study highlights the effectiveness of fluralaner and fipronil in inhibiting specific GABA receptors in FAW, indicating potential strategies for the rotation of these insecticides in agriculture to manage pest resistance.