Publications by authors named "Emre Tam"
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky Amal Kamal Abdel-Aziz Sara Abdelfatah Mahmoud Abdellatif Asghar Abdoli Tamar Avin-Wittenberg Gautam Borthakur Tamas Csizmadia Tamar Farfel-Becker Katsuhiko Kitamoto Tamas Korcsmaros Laura Santambrogio Chit Tam Shing Yau Tam Davide Tampellini Atsushi Tamura Gianluca Tettamanti Tamotsu Yoshimori
Autophagy
January 2021
Article Synopsis
- In 2008, guidelines were established for researching autophagy, which has since gained significant interest and new technologies, necessitating regular updates to monitoring methods across various organisms.
- The new guidelines emphasize selecting appropriate techniques to evaluate autophagy while noting that no single method suits all situations; thus, a combination of methods is encouraged.
- The document highlights that key proteins involved in autophagy also impact other cellular processes, suggesting genetic studies should focus on multiple autophagy-related genes to fully understand these pathways.
The sequenced members of a novel family of small, hydrophobic, bacterial multidrug-resistance efflux proteins, which we have designated the small multidrug resistance (SMR) protein family, are identified and analysed. Two distinct clusters of proteins were identified within this family: (i) small multidrug efflux systems; and (ii) Sug proteins, potentially involved in the suppression of groEL mutations. Hydropathy and residue distribution analyses of this family suggest a structural model in which the polypeptide chain spans the membrane four times as mildly amphipathic alpha-helices.
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