The Role of EREG, PTPN1, and SERPINB7 Genes in the Pathogenesis of Psoriasis: May SERPINB7 Be Protective and a Marker of Severity for Psoriasis?

Introduction: Psoriasis is a chronic inflammatory dermatological disease with complex pathogenesis in which many immune system cells, including keratinocytes, play a role. Many genes regulate the proliferation of keratinocytes and other immune cells that have essential roles in the pathogenesis of psoriasis. The expressions of EREG, PTPN1, and SERPINB7 genes were shown as upregulated in psoriatic skins in a few studies previously.

Evaluation of health anxiety in adults admitting to primary healthcare institutions.

Objective: Health anxiety is defined as the negative over-interpretation of the usual physical sensations, although the person does not have any physical illness. The study aims to evaluate the health anxiety levels of individuals over the age of 18 who admit to primary healthcare institutions in Eskisehir and the factors that may be associated with it.

Methods: This is a cross-sectional study.

Assessment of hearing loss in patients with rosacea.

Objectives/aims: Rosacea is not only a skin condition but a systemic inflammatory disease that includes chronic inflammation, vascular alterations, and autoimmunity in pathogenesis. We aimed to evaluate the presence of a sensorineural hearing loss in the patients with rosacea in comparison with the healthy control group and, also to compare the audiometric results according to the severity of disease among the patient group.

Methods: Fifty-three patients with erythematelangiectatic or papulopustular type of rosacea and 105 age- and sex-matched healthy controls were included.

Elderly people's quality of life in rural areas of Turkey and its relationship with loneliness and sociodemographic characteristics.

Background: The aim of the present study was to examine the relationships between loneliness, quality of life and the factors that may be related to the quality of life in individuals ≥65 years old living in rural areas of Turkey.

Methods: The World Health Organization Quality of Life Instrument Older Adults Module (WHOQOL OLD) and Loneliness Scale for the Elderly (LSE) was administered to 427 elderly participants. Multiple linear regression was used to determine the variables that affected QOL.

Prevalence of early-onset androgenetic alopecia and its relationship with lifestyle and dietary habits.

Background: Early-onset androgenetic alopecia (AGA) is the most common cause of alopecia in men under 30 years of age; however, its prevalence and non-genetic risk factors are not well documented. The aim of our study was to determine the early-onset AGA prevalence and to evaluate its relationship with lifestyle and dietary habits.

Methods: This study was conducted on 1507 male university students aged 18-30 years.

Prevalence of onychophagia and its relation to stress and quality of life.

Introduction: Onychophagia is defined as putting one's fingers into the mouth and biting the nails. We sought to evaluate the prevalence of onychophagia in university and high school students and its relation to sociodemographic factors, perceived stress, and quality of life.

Methods: A total of 3,475 students were included in the study.

The evaluation of vitamin K status in children with febrile seizure.

Background: Febrile seizure is the most common neurological disorder in childhood. The exact pathophysiology of febrile seizures is unknown. Recent studies showed the role of vitamin K in nonhematological and inflammatory disorders.

The effect of exercise prescription of primary care physician on the quality of life in patients.

Purpose: The aim of this study was to examine the effect of exercise prescribed by primary care physicians (PCPs) on the quality of life (QoL) of elderly people.

Method: Randomisation was performed at PCPs level from 16 primary healthcare centers. Patients were divided into intervention and control groups.

Menstruation-related headache in adolescents: Point prevalence and associated factors.

Background: The aim of this study was to investigate the prevalence of menstruation-related headache and the impact of associated factors in adolescents.

Methods: This cross-sectional study was conducted in seven randomly selected high schools, and 3,886 girls attending those schools were invited to take part. After the consent of the school principals, a final total of 2,485 girls (63.

Investigation of the effect of changes in muscle strength in gestational age upon fear of falling and quality of life.

Background/aim: The aim of this study is the investigation of the effect of changes in muscle strength in gestational age upon fear of falling and quality of life.

Materials And Methods: This longitudinal, descriptive study included a sample of 37 pregnant women who volunteered to participate. The research data were collected at 20 and 32 weeks of gestation.

Prevalence of Sport Injuries among Middle School Children and Suggestions for Their Prevention.

[Purpose] The purpose of this study was to determine the incidence of injuries of children participating in sports, and to present advice on injury prevention. [Subjects and Methods] The study subjects were 445 children involved in sports with a mean age of 12.74±1.