Computer-aided detection improves detection of pulmonary nodules in chest radiographs beyond the support by bone-suppressed images.

Purpose: To evaluate the added value of computer-aided detection (CAD) for lung nodules on chest radiographs when radiologists have bone-suppressed images (BSIs) available.

Materials And Methods: Written informed consent was waived by the institutional review board. Selection of study images and study setup was reviewed and approved by the institutional review boards.

Role of radiography, MRI and FDG-PET/CT in diagnosing, staging and therapeutical evaluation of patients with multiple myeloma.

Multiple myeloma is a malignant B-cell neoplasm that involves the skeleton in approximately 80% of the patients. With an average age of 60 years and a 5-years survival of nearly 45% Brenner et al. (Blood 111:2516-2520,35) the onset is to be classified as occurring still early in life while the disease can be very aggressive and debilitating.