Publications by authors named "Emmanuelle Sandra Adjoa Ametepe"
Whole genome sequencing of M. tuberculosis for disease control in high-burden settings: study protocol for a cluster randomized controlled trial evaluating different community-wide intervention strategies in rural Madagascar.
Emmanuelle Sandra Adjoa Ametepe Noela Andriamanoha Fanantenana Randria Andrianomanana Floriane Point Reziky Tiandraza Mangahasimbola
Trials
October 2024
Article Synopsis
- The study explores the potential benefits of using whole genome sequencing of Mycobacterium tuberculosis to improve tuberculosis case detection in high-incidence areas, as previous research has shown its effectiveness in identifying outbreaks and transmission events.* -
- A cluster randomized controlled trial will take place in 48 rural village groups in Madagascar, comparing three intervention methods: standard care with microscopy, active case finding with PCR testing, and a novel approach that includes both PCR testing and genome sequencing.* -
- The primary goal is to assess the number of tuberculosis cases detected per 100,000 people after one year of different interventions, aiming to enhance understanding of how genomic tracking can improve tuberculosis management in regions with high disease levels.*