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Publications by authors named "Emmanuelle N St Jean"

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Evidence for a Trypanosoma brucei lipoprotein scavenger receptor.
Heather P Green Maria Del Pilar Molina Portela Emmanuelle N St Jean Elena B Lugli Jayne Raper

J Biol Chem

January 2003

African trypanosomes are lipid auxotrophs that live in the bloodstream of their human and animal hosts. Trypanosomes require lipoproteins in addition to other serum components in order to multiply under axenic culture conditions. Delipidation of the lipoproteins abrogates their capacity to support trypanosome growth.

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Synopsis of recent research by authors named "Emmanuelle N St Jean"

  • Emmanuelle N St Jean's research primarily focuses on the interactions between African trypanosomes and lipoproteins, examining how these parasites acquire essential lipids from their hosts.
  • In her 2003 publication, she presents evidence for a lipoprotein scavenger receptor in Trypanosoma brucei, highlighting the parasite's dependence on these molecules for survival and proliferation in the bloodstream.
  • The findings indicate that delipidation of lipoproteins significantly impairs their ability to support trypanosome growth, underscoring the critical role of lipoproteins in the parasitic life cycle.

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