Spectroscopic exploration of mode of binding of DNA and BSA with acridone alkaloids isolated from (Rutaceae).

is a medicinal plant widely studied due to its great phytochemical diversity, especially its acrinonic alkaloids, which have shown to be promising anticancer candidates. The aim of this work was to promote the isolation of acridonic alkaloids from fruits of and carried out absorption and fluorescence spectroscopy studies with calf thymus DNA and BSA. Five acridone alkaloids have been isolated, including the first description of 3-desmethoxy arborinine ().

Antiproliferative activity of semisynthetic xylopic acid derivatives.

Two -kaurene diterpenoids, -15--acetyloxy-kaur-16-en-19-oic acid (xylopic acid) and -7-oxo-kaur-16-en-19-oic acid were isolated from the fruits of . Chemical manipulation of xylopic acid yielded -kaurane derivatives , , , and . Their structures were elucidated by spectroscopic analysis, including 1 D- and 2 D-NMR spectroscopies.