Antibacterial activity of natural flavones against bovine mastitis pathogens: in vitro, SAR analysis, and computational study.

Unlabelled: Bovine mastitis is a worldwide disease affecting dairy cattle and causes major economic losses in the dairy industry. Recently, the emergence of microbial resistance to the current antibiotics complicates the treatment protocol which necessitates antibiotic stewardship and further research to find new active compounds. Recently, phytobiotics have gained interest in being used as an alternative to antibiotics in the poultry industry as an antibiotic stewardship intervention.

Isolation and characterization of new phenolic siderophores with antimicrobial properties from sp. UIAU-6B.

Five new phenolic siderophores - were isolated from the organic extract of a culture broth in a modified SGG medium of sp. UIAU-6B, obtained from sediments collected from the Oyun river in North Central Nigeria. The structure of the new compounds, pseudomonin A-C (-) and pseudomobactin A and B ( and ) isolated alongside two known compounds, pseudomonine () and salicylic acid (), were elucidated based on high-resolution mass spectrometry, 1D and 2D NMR analyses.