Publications by authors named "Emmanuel Tiret"

Background: The wide global variation in the definition of the rectum has led to significant inconsistencies in trial recruitment, clinical management, and outcomes. Surgical technique and use of preoperative treatment for a cancer of the rectum and sigmoid colon are radically different and dependent on the local definitions employed by the clinical team. A consensus definition of the rectum is needed to standardise treatment.

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Background Information: We aimed to compare prospectively the complications and functional outcome of patients undergoing a J-Pouch (JP) or a side-to-end anastomosis (SE) for treatment of low rectal cancer at a 2-year time point after resection for rectal cancer.

Methods: A multicenter study was conducted on patients with low rectal cancer who were randomized to receive either a JP or SE and were followed for 24 months utilizing SF-12 and FACT-C surveys to evaluate the quality of life (QOL). Fecal incontinence was evaluated using the Fecal Incontinence Severity Index (FISI).

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Background: C-reactive protein is a useful negative predictive test for the development of anastomotic leakage following colorectal surgery. Evolution of procedures (laparoscopy, enhanced recovery program, early discharge, complex redo surgery) may influence C-reactive protein values; however, this is poorly studied to date.

Objective: The aim of this study is to evaluate C-reactive protein as an indicator of postoperative complication and as a predictor for discharge.

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Background: Postoperative peritonitis (POP) following gastrointestinal surgery is associated with significant morbidity and mortality, with no clear management option proposed. The aim of this study was to report our surgical management of POP and identify pre- and perioperative risk factors for morbidity and mortality.

Methods: All patients with POP undergoing relaparotomy in our department between January 2004 and December 2013 were included.

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Purpose: The high morbidity rates reported might influence surgeons' decisions of whether to perform Hartmann's reversal (HR). Our aim was to report the results of HR after "primary" Hartmann's procedure (HP) or in redo surgery for failed anastomosis.

Methods: All patients operated between 2007 and 2015 were included.

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Article Synopsis
  • Regular follow-up for Lynch syndrome (LS) patients is crucial due to their high risk of developing colorectal and other cancers, but there's no consensus on the optimal timing for colonoscopies after a first cancer.
  • A study followed 121 LS patients with a primary colorectal cancer, finding that 32.2% experienced metachronous cancers, typically emerging within 24 months post-colonoscopy.
  • The findings suggest that surveillance colonoscopies should occur at least every 18 months, particularly for those with MSH2 mutations, to manage the increased risk of additional cancers.
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Background: Despite the effectiveness of anti-TNF alpha (ATA) treatment to induce and maintain remission in Crohn's disease, surgical intervention is frequently required. Results of previous studies on the impact of anti-TNF on postoperative course are discordant. The aim of this study was to evaluate the impact of ATA on postoperative morbidity following ileocolic resection for Crohn's disease.

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Background: Duodenal polyposis is a manifestation of adenomatous polyposis that predisposes to duodenal or ampullary adenocarcinoma. Duodenal polyposis is monitored by upper GI endoscopies and may require iterative resections and prophylactic radical surgical treatment when malignancy is threatening.

Objective: The purpose of this study was to evaluate severity scoring for surveillance and treatment in a large series of duodenal polyposis.

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Background: Assessing the satisfaction of patients about the health care they have received is relatively common nowadays. In France, the satisfaction questionnaire, I-Satis, is deployed in each institution admitting inpatients. Internet self-completion and telephone interview are the two modes of administration for collecting inpatient satisfaction that have never been compared in a multicenter randomized experiment involving a substantial number of patients.

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Objectives: To determine the cumulative incidence and the prognostic factors of ileorectal anastomosis (IRA) failure after colectomy for ulcerative colitis (UC).

Background: Although ileal pouch-anal anastomosis is recommended after colectomy for UC, IRA is still performed.

Methods: This was a multicenter retrospective cohort study, which included patients with IRA for UC performed between 1960 and 2014.

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Purpose A pathologic complete response (pCR; ypT0N0) of a rectal tumor after neoadjuvant radiochemotherapy (RCT) is associated with an excellent prognosis. Several retrospective studies have investigated the effect of increasing the delay after RCT. The aim of this study was to evaluate the effect of increasing the interval between the end of RCT and surgery on the pCR rate.

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Purpose: A potential complication in women after ileal pouch-anal anastomosis (IPAA) is sexual impairment and reduced fertility. The aim was to evaluate sexual function and fertility after IPAA.

Methods: All female patients who underwent an IPAA between 2004 and 2013 were retrospectively included.

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Purpose: Evaluation of urinary drainage after rectal resection and identification of criteria associated with postoperative urinary dysfunction (UD). UD remains a clinical problem for up to two thirds of patients after rectal resection. Currently, there are no guidelines concerning duration or type of drainage.

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Objectives: To assess mortality after restorative proctocolectomy (RPC) and determine the influencing factors with a specific focus on institutional caseload and surgical approach in France.

Background: RPC is an uncommonly performed and demanding procedure; case volume may exert a significant influence on outcome.

Methods: Data of all patients who underwent RPC in France between 2009 and 2012, including demographics, diagnosis, procedures, mode of admission, discharge, and hospital type were collected.

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Introduction: The surgical approach for the treatment of tumors of the upper third of the rectum remains controversial. Several publications have shown that partial excision of the mesorectum (PME) with division of the mesorectum and rectum 5 cm below the tumor could be a reasonable approach although total mesorectal excision (TME) is still considered the gold standard for all rectal cancers in many studies. We aimed to assess the specifics risks of anterior resection with PME and colorectal anastomosis (CRA) in rectal cancer.

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Background: Stoma reversal can be performed during liver resection (LR) in patients with colorectal liver metastases (CRCLM) whose primary colorectal tumor has been previously resected with a diverting loop ileostomy. This combined procedure is reputed to be associated with an increased morbidity. This study investigates the impact of simultaneous loop ileostomy closure (LIC) on the postoperative outcome of LR for CRCLM.

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Background: After rectal resection for adenocarcinoma, pathological examination may reveal invasion of the distal margin (DM) and/or a circumferential resection margin of the tumor (CRM-T) or of involved nodes (CRM-N) less than or equal to 1 mm. Such findings transform a planned R0 resection to R1.

Aim: : The aim was to analyze the impact of an R1 resection on prognosis, recurrence rate, and choice of adjuvant treatment.

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No guidelines for desmoid tumors (DT) management are available and DT have now become the first cause of death in FAP patients who had restorative proctocolectomy. We aimed to assess the results of the different treatments used for DT in Familial Adenomatous Polyposis (FAP) patients. All patients followed for FAP who developed a DT between 1970 and 2010 were collated.

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Background: Standard operative management of colorectal cancer (CRC) with adherent adjacent organs is en bloc resection to obtain clear resection margins. We analyzed early and long-term outcomes after multivisceral resection for clinically suspected T4 CRC and identified factors predicting survival.

Methods: All patients operated on for clinically suspected T4 CRC between 2000 and 2010 were identified retrospectively.

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Objective: Establish a protocol of management of acute appendicitis (AA) in ambulatory surgery (AmbSurg) on the basis of preoperative criteria.

Background: Ambulatory laparoscopic appendectomy (LA) for AA has not been yet reported.

Methods: All patients who underwent LA between 2010 and 2012 were reviewed.

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