Genetic Association Between Growth Differentiation Factor 5 Single Nucleotide Polymorphism and Primary Knee Osteoarthritis in a Group of Egyptian Patients: A Pilot Study.

Aim: This study aimed to determine the genetic association between Growth Differentiation Factor 5 (GDF5) gene (rs143383 T/C) single nucleotide polymorphism (SNP) and primary knee osteoarthritis (OA) in a group of Egyptian patients.

Patients And Methods: The study included 47 patients with primary knee OA and 40 apparently healthy control subjects. The disease was assessed using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score and Health Assessment Questionnaire (HAQ).

Efficient and Robust Skeleton-Based Quality Assessment and Abnormality Detection in Human Action Performance.

Elderly people can be provided with safer and more independent living by the early detection of abnormalities in their performing actions and the frequent assessment of the quality of their motion. Low-cost depth sensing is one of the emerging technologies that can be used for unobtrusive and inexpensive motion abnormality detection and quality assessment. In this study, we develop and evaluate vision-based methods to detect and assess neuromusculoskeletal disorders manifested in common daily activities using three-dimensional skeletal data provided by the SDK of a depth camera (e.

A general descriptor for detecting abnormal action performance from skeletal data.

We propose an action-independent descriptor for detecting abnormality in motion, based on medically-inspired skeletal features. The descriptor is tested on four actions/motions captured using a single depth camera: sit-to-stand, stand-to-sit, flat-walk, and climbing-stairs. For each action, a Gaussian Mixture Model (GMM) trained on normal motions is built using the action-independent feature descriptor.

Transcutaneous posterior tibial nerve electrostimulation with low dose trospium chloride: Could it be used as a second line treatment of overactive bladder in females.

Aim: To evaluate the effect of adding low dose trospium chloride with transcutaneous posterior tibial nerve stimulation (TPTNS) in the treatment of overactive bladder (OAB) in females after failure of behavioral therapy.

Methods: We randomized 30 women with OAB, in two groups: G I received 30 min TPTNS, three times a week; GII received TPTNS plus 20 mg trospium chloride daily. OAB Symptom Score questionnaire (OABSS), Incontinence Impact Questionnaire-short form 7 (IIQ-7), 3 day voiding diary and urodynamics at weeks 0 and 8 were evaluated.