Publications by authors named "Emmanuel Petroulakis"
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Synopsis of recent research by authors named "Emmanuel Petroulakis"
Emmanuel Petroulakis’ research focuses on the mechanisms of translational control and its implications for cell proliferation, survival, and tumorigenesis, primarily through the regulation of key initiation factors and the mTOR signaling pathway.
Notable findings include the identification of La-related Protein 1 (LARP1) as a novel target of mTORC1 that is fundamental to terminal oligopyrimidine mRNA translation, highlighting the complexity of mTORC1’s role in protein synthesis.
Other studies reveal how translational repressors, such as 4E-BPs, influence somatic cell reprogramming and cancer progression, emphasizing the critical balance between translation and cellular processes in both normal physiology and disease.
