In-Field Implementation of Near-Infrared Quantitative Methods for Analysis of Medicines in Tropical Environments.

Near-infrared (NIR) spectroscopy is actually a well-established technique that demonstrates its performance in the frame of detection of poor-quality medicines. The use of low-cost handheld NIR spectrophotometers in low-resource contexts can allow an inexpensive and more rapid detection compared to laboratory methods. Considering these points, it was decided to develop, validate, and transfer methods for the quantification of ciprofloxacin and metronidazole tablet samples using a NIR handheld spectrophotometer in transmission mode (NIR-M-T1) coupled to chemometrics such as partial least squares regression (PLSR) algorithm.

Evaluation of the Antimicrobial Resistance Surveillance System in Sentinel Sites in Cameroon.

Background The purpose of antimicrobial resistance (AMR) surveillance is to guide clinical decision-making, characterize trends in resistance infections, and provide epidemiological data to study the impact of AMR on health and the effectiveness of control measures in health facilities and the community. To do this, regular and relevant assessments of standardized AMR surveillance systems are essential to prioritize threats and improve their performance and cost-effectiveness. The scarcity of data and the absence of a local and national strategy on the surveillance of antibiotic resistance in Sub-Saharan Africa and even more so in Cameroon do not allow an effective response to be carried out against the scourge.

Antibiotic consumption history of patients in a referred laboratory in Yaounde.

Background: Regulation of antibiotic prescription and consumption remains a major public health burden in low- and middle- income countries.

Objective: This study aimed to describe the antibiotic consumption of patients who had a positive antibiotic culture in a reference laboratory.

Methods: A retrospective descriptive study was conducted among 113 participants with positive antibiograms with a documented history of antibiotics intake at the Yaoundé University Teaching Hospital in Cameroon between January 2016 and June 2021.

[Not Available].

Objective: We sought to evaluate ginger's cardiovascular and metabolic effects (Zingiberofficinale) add-on therapy in type 2 diabetes patients over six weeks.

Methods: We performed a single-arm clinical trial. In well-to-moderately controlled Type 2 diabetic patients with unchanged treatment for at least three months, the intervention consisted of 6-week add-on oral supplementation of powdered ginger extracts in capsules at a dose of 399 mg three times per day.

Poor-Quality Medicines in Cameroon: A Critical Review.

Poor-quality medicines are the cause of many public health and socioeconomic problems. We conducted a review to acquire an overview of the situation concerning such medicines in Cameroon. Different searches were performed on databases from several websites of the WHO, the Ministry of Public Health of Cameroon, the Anti-Counterfeit Medicine Research Institute, the Global Pharma Health Fund, and the Infectious Disease Data Observatory.

Knowledge, practices and attitudes on antibiotics use in Cameroon: Self-medication and prescription survey among children, adolescents and adults in private pharmacies.

Benefits of antibiotics are threatened by the self-medication, people's lack of knowledge and inappropriate use of antibiotics, especially in developing countries. This study was designed to determine knowledge; attitudes and practices toward antibiotics use in an urban community, and evaluate the factors that are associated with antibiotic use. Between January and March 2015, a cross sectional and prospective study was conducted in all pharmacies within the Douala IV health district, Cameroon.